MS4A6A gene application

An MS4A6A and gene technology, applied in the field of MS4A6A gene, can solve the problems of no significant increase in sensitivity, low sensitivity, and long time consumption.
CN103074422AInactive Publication Date: 2013-05-01THE THIRD PEOPLES HOSPITAL OF SHENZHEN

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
THE THIRD PEOPLES HOSPITAL OF SHENZHEN
Publication Date
2013-05-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides an MS4A6A gene application, and relates to the preparation of products to distinguish latent tuberculosis infection and active tuberculosis. The preferred products include the products utilizing real-time quantitative PCR or gene chip detection to distinguish the latent tuberculosis infection and the active tuberculosis. According to the experimental results, the expression of the MS4A6A gene is obviously higher in the blood of tuberculosis patients than in healthy people or latent infection crowds, and therefore, the MS4A6A gene can serve as a special marking gene for the diagnosis of tuberculosis, so as to allow the tuberculosis diagnosis to be more accurate and quicker.
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Description

technical field

[0001] The invention relates to the technical field of bioengineering, in particular to the application of MS4A6A gene. Background technique

[0002] Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis infection. Mycobacterium tuberculosis can not only cause pulmonary tuberculosis (85%), but also cause tuberculosis in multiple organs outside the lungs. Although there are currently effective anti-tuberculosis drugs, tuberculosis is still the number one killer of infectious diseases, and about 2 million people die from tuberculosis every year in the world; about one-third of the world's population is infected with Mycobacterium tuberculosis, which is called About 10% of people with latent tuberculosis infection (LTBI) will eventually develop active tuberculosis.

[0003] Due to the lack of effective tuberculosis vaccine, the prevention and control of tuberculosis mainly depends on early detection, treatment and isolation of a...

Claims

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