Preparation method for ivermectin solution used for fowls

The technology of ivermectin and solution is applied in the field of preparation of ivermectin solution for poultry, which can solve the problems of farmers being unable to self-administer drugs, increasing farmers' expenses, inconvenient use, etc., so as to reduce breeding costs and reduce Labor consumption, easy-to-achieve effects

Inactive Publication Date: 2013-05-08
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Concentrated feed mixing is extremely inconvenient for the majority of farmers, and requires a lot of manpower and material resources. For the mix, it is easy to mix the mix unevenly, which brings great side effects
Administration by injection requires certain veterinary experience, and most farmers cannot administer the drug by themselves, so they need to hire a specialized veterinarian, which increases the cost of farmers

Method used

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  • Preparation method for ivermectin solution used for fowls

Examples

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Comparison scheme
Effect test

Embodiment 1

[0014] Take 10L of 95% ethanol and dissolve 0.5kg of ivermectin in a water bath at 70°C. After ivermectin is dissolved, add Tween-802L, stir evenly, add dimethylformamide to 100L, stir evenly, keep for 15-20min, and make ivermectin solution for poultry after the liquid is clear .

Embodiment 2

[0016] Take 20 L of 95% ethanol and dissolve 5 kg of ivermectin in a 70° C. water bath. After ivermectin is dissolved, add Tween-80 10L, stir evenly, add dimethylformamide to 100L, stir evenly, keep for 15-20min, and make ivermectin for poultry after the liquid is clear solution.

Embodiment 3

[0018] Take 12L of 95% ethanol and dissolve 0.8kg of ivermectin in a water bath at 70°C. After ivermectin is dissolved, add Tween-80 3L, stir evenly, add dimethylformamide to 100L, stir evenly, keep for 15-20min, and make ivermectin for poultry after the liquid is clear solution.

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Abstract

The invention discloses a preparation method for an ivermectin solution used for fowls, so as to make the ivermectin solution mix with water easily and be administered by drinking water, to guarantee accuracy of dosage and to prevent side effects brought by unevenly mixed materials. The preparation method comprises the steps of taking 10-20 L of 95% ethanol and, dissolving 0.5-5 kg of ivermectin in a water bath at a temperature of 70 DEG C, adding 2-10 L of Tween-80 after the ivermectin is dissolved, stirring uniformly, adding dimethylformamide to a total volume of 100 L, keeping for 15-20 min after uniformly stirring, thus obtaining the ivermectin solution used for the fowls after the solution is clarified. The 95% ethanol is used as a solvent and the ivermectin is dissolved in a water bath, so that the added Tween-80 has an emulsification effect and then is mixed with dimethylformamide. The obtained solution has an effect of mixing with water in any proportion. The ivermectin solution is administrated by drinking water, so that accuracy of dosage can be guaranteed; and the ivermectin solution is convenient for use and reduces labor force consumption. Besides, side effects brought by unevenly mixed materials can be prevented.

Description

technical field [0001] The invention relates to a preparation method of ivermectin solution for poultry. Background technique [0002] Poultry parasite infection is a common disease, and its infection has two categories: internal and external parasites. Parasites can cause adverse reactions such as reduced feed conversion rate, growth retardation, aggravated stress response, infectious diseases, and affected appearance of poultry. Ivermectin is a broad-spectrum anti-parasite drug, which has anti-parasite effects on both internal and external parasites, and is widely used in the anti-parasite killing. Ivermectin can be administered orally and by injection to achieve the killing effect. [0003] However, the dosage of ivermectin is extremely low. Generally, for poultry, it is about 0.3mg per 1kg of body weight, and under normal circumstances, ivermectin is insoluble in water, so injection medicine or concentrated mixing materials are used for feeding. It is extremely inconv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K31/704A61K47/34A61P33/00A61P33/14
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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