Novel drug composition for curing hepatitis c virus

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problem of lower infection efficiency of hepatitis C virus
CN103127511AInactive Publication Date: 2013-06-05WATERSTONE PHARMA WUHAN

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
WATERSTONE PHARMA WUHAN
Publication Date
2013-06-05
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a novel antiviral drug composition and a method for curing hepatitis c virus (HCV) infection by using the novel type antiviral drug composition. The novel antiviral drug composition comprises 1 - (4-fluorine phenyl) - (3R)- [3 - (4 - fluorine phenyl) - (3S) - hydroxypropyl] - (4S) - (4 - hydroxypropyl) - 2-acrylic amide (ezetimibe, structural formula presented as graph 1) or acceptable derivatives in pharmaceutic preparation thereof, and an HCV resisting drug which is a drug composition selected from one kind or multiple kinds of boceprecir (BOC), telaprevir (TVR), pegylated interferon alpha (PEG - IFN alpha), interferon (IFNO) and ribavirin.
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Description

Technical field:

[0001] The present invention relates to a novel antiviral pharmaceutical composition, which comprises 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]- (4S)-(4-hydroxyphenyl)-2-propanolactam (ezetimibe, Ezetimibe, structural formula see figure 1 ) or its pharmaceutically acceptable derivatives, and anti-HCV (hepatitis C virus) drugs are selected from Boceprevir (BOC), Telaprevir (TVR), long-acting interferon (PEG-IFNα ), interferon (IFNα), ribavirin (Ribavirin) one or more of the pharmaceutical composition and the method for treating HCV infection, belong to the field of pharmaceutical preparations. Background technique:

[0002] Hepatitis C virus, referred to as hepatitis C, hepatitis C, is a kind of viral hepatitis caused by hepatitis C virus (Hepatitis C virus, HCV) infection, mainly through blood transfusion, acupuncture, drug abuse, etc., according to the World Health Organization Organization statistics show that the global HCV infecti...

Claims

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