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Double-layer cell co-culture device with adjustable gap

A cell culture and co-cultivation technology, which is applied in the direction of tissue cell/virus culture devices, biochemical instruments, biochemical equipment and methods, etc., can solve the problems of single experimental results, and achieve the purpose of promoting cell proliferation, promoting growth and value-added, and maintaining cell The effect of biological function

Active Publication Date: 2014-06-11
INST OF MECHANICS - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the co-culture between cells with fixed spacing is mainly used, and there is a problem of single experimental results in the cell co-culture experiment

Method used

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  • Double-layer cell co-culture device with adjustable gap
  • Double-layer cell co-culture device with adjustable gap
  • Double-layer cell co-culture device with adjustable gap

Examples

Experimental program
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Embodiment Construction

[0015] Such as figure 1 As shown, the present invention includes: a cell culture box 1, a cell culture tank 2 and a driving part 3, and the cell culture box 1 is used for culturing the first cells. The cell culture tank 2 is used for cultivating the second cells, and the cell culture tank 2 is movably arranged in the cell culture box 1 . The driving part 3 is used to drive the cell culture tank 2 to move to the bottom of the cell culture box 1 in the cell culture box 1 to adjust the gap between the bottom of the cell culture box 1 and the bottom of the cell culture tank 2 to a predetermined distance.

[0016] Such as figure 1 As shown, in the embodiment of the present invention, the cell culture box 1 is provided with a side wall 11 , and a spring pick 12 elastically supporting the cell culture tank 2 is formed on the side wall 11 . One end of the spring plectrum 12 is formed on the side wall 11 , and the other end is formed with a tab 13 for supporting the cell culture tank...

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Abstract

The invention discloses a double-layer cell co-culture device with an adjustable gap. The double-layer cell co-culture device comprises a cell culture box, a cell culture groove and a driving part, wherein the cell culture box is used for culturing a first cell; the cell culture groove is used for culturing a second cell, and is arranged in the cell culture box in a removable manner; and the driving part drives the cell culture groove to move to the bottom of the cell culture box in the cell culture box, and can adjust the gap between the bottom of the cell culture box and the bottom of the cell culture groove to the predetermined distance. According to the double-layer cell co-culture device provided by the invention, the driving part drives the cell culture groove to move to the bottom of the cell culture box, and thus, the distance between the double layers of cells is adjusted in an on-line manner, the gap can adjust the growth and the function of the cells, so that the adjustable growing environment is provided for cell co-culture, and the feasible device is provided for exploring a cell co-culture technology.

Description

technical field [0001] The invention relates to a cell co-cultivation device for cell biology, biomedicine and biomechanics research. Background technique [0002] Co-cultivation technology is to culture two or more types of cells together in the same growth environment, and requires different cell layers to be cultured so that different cells can interact and grow together. For example, when studying human hepatocytes, co-culture of multiple cells is required. [0003] At present, the co-culture between cells with fixed spacing is mainly used, and there is a problem of single experimental results in the cell co-culture experiment. Contents of the invention [0004] In view of the problems existing in the prior art, the purpose of the present invention is to provide a double-layer cell co-culture device with adjustable gap, the distance between the two layers of cells can be adjusted online, and the regulation of the gap on cell growth and its function can be realized. P...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M3/00
Inventor 龙勉高宇欣罗春花上官冰
Owner INST OF MECHANICS - CHINESE ACAD OF SCI
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