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Prophylactic or therapeutic drug for peripheral neuropathy caused by anticancer agent

A technology for peripheral neuropathy and anticancer agents, which is applied in the directions of nervous system diseases, anti-inflammatory agents, and antitumor agents to achieve excellent pharmacological effects and high usefulness.

Inactive Publication Date: 2013-10-02
NIPPON ZOKI PHARM CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the neurotrophic factor-like agent in Patent Document 1 only describes that it is useful as a preventive / improving agent for neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, and mental diseases such as depression and anxiety (neurosis). However, there is no description on the prevention or treatment of peripheral neuropathy caused as a side effect of anticancer agents in the present invention

Method used

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  • Prophylactic or therapeutic drug for peripheral neuropathy caused by anticancer agent
  • Prophylactic or therapeutic drug for peripheral neuropathy caused by anticancer agent
  • Prophylactic or therapeutic drug for peripheral neuropathy caused by anticancer agent

Examples

Experimental program
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Effect test

Embodiment

[0070] The following shows an example of the results of pharmacological tests related to the novel pharmacological action of the agent of the present invention, that is, the effect of preventing or treating peripheral neuropathy caused by administration of an anticancer agent, but the present invention is not limited by the description of these examples. any restrictions.

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Abstract

The purpose of the present invention is to provide an effective drug for the prevention or treatment of peripheral neuropathy developed as a side effect of the administration of an anticancer agent. This invention provides a drug containing a C10 fatty acid ester as an effective component thereof, for the prevention or treatment of peripheral neuropathy arising from the administration of a drug including at least one type of anticancer agent. This drug having said compound as the effective component thereof is highly useful as a drug for the prevention or treatment of peripheral neuropathy caused by the administration of the anticancer agent.

Description

technical field [0001] The present invention relates to a novel medical use of an ester of a fatty acid having 10 carbon atoms, in particular to a medicament containing a drug for preventing or treating peripheral neuropathy caused by administration of a medicament containing at least one anticancer agent The esters of fatty acids with 10 carbon atoms are used as active ingredients. Background technique [0002] Currently, in the treatment of cancer (malignant tumor), surgery, radiation exposure, and chemotherapy are preferably used alone or in combination. Among them, anticancer agents (anti-malignant tumor agents) used in chemotherapy are inherently cytotoxic, and damage not only cancer cells but also normal human cells, thereby causing side effects. It is important to administer the drug in a manner that exhibits a sufficient anticancer effect while having such side effects. [0003] Side effects accompanying the administration of anticancer agents involve many aspects ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/201A61P25/02
CPCA61K31/23A61K31/231A61K9/0019A61K9/0095A61K9/10A61K45/06B82Y5/00A61K47/6951A61P25/02A61P29/00A61P35/00A61K31/201C07C69/533
Inventor 饭沼宗和古川昭荣内木充冈田智行松元智规泽田和好
Owner NIPPON ZOKI PHARM CO LTD
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