Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of ludwigia octovalvis extract in preparing composition for enhancing memory function and relieving neurodegeneration

A technology that enhances memory and neurodegeneration, and is applied in drug combinations, nervous system diseases, medical preparations containing active ingredients, etc., and can solve the problems of inaccurate diagnosis and effective treatment of Alzheimer's disease

Active Publication Date: 2014-02-12
SUN PLAZA INT
View PDF3 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There is still no accurate diagnosis and effective treatment for Alzheimer's disease, so scientists all over the world are devoting themselves to the research and development of new drugs or treatments

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of ludwigia octovalvis extract in preparing composition for enhancing memory function and relieving neurodegeneration
  • Application of ludwigia octovalvis extract in preparing composition for enhancing memory function and relieving neurodegeneration
  • Application of ludwigia octovalvis extract in preparing composition for enhancing memory function and relieving neurodegeneration

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0044] Example 1: Preparation of Water Clove Extract

[0045] Firstly, grind the cloves and immerse them in the extraction working liquid at a low temperature of 2-10°C for 4-12 hours, and then heat them at a temperature of 50-100°C for 10-60 minutes to obtain the extract and residue of cloves . The working liquid is water or ethanol solution. Then, the residue was separated by centrifugal filtration. Next, the separated residue is immersed in another extraction working liquid, and the extraction working liquid is heated at a temperature of 50-100°C for 10-60 minutes and then centrifugally filtered to produce a secondary extract of cloves monohydrate , and then dissolve the water clove secondary extract into the water clove extract. After that, use a drying process to dry the water clove extract to a water clove extract; wherein, when the extraction working liquid is water, freeze-drying can be used, and when the extraction working liquid is ethanol solution, decompression ...

example 2

[0046] Example 2: Water clove extract improves memory function

[0047] Drosophila learning and memory experiment (Pavlovian olfactory associative learning & memory) was used to study the effect of water clove extract on memory function, mainly using the way of Drosophila olfactory aversion learning to teach Drosophila to remember the association between odor and slight electric shock stimulation : Giving an electric shock when the fruit fly smells a smell, and then the fruit fly will run away when it smells the smell, so as to get a correct score, so as to judge the learning and memory function based on this test. The fruit flies were raised in an environment of 25°C, and the fruit flies were divided into four groups. The concentration of clove extract contained in the food fed to the control group was 0%, and the concentration of clove extract contained in the food fed to the experimental group was respectively 0.005%, 0.01% and 0.1%, on the 20th day, the learning and memory...

example 3

[0048] Example 3: Water clove extract delays neurodegeneration

[0049] Experiments were carried out on 3-month-old progeria mice (senescence-accelerated mouse prone-8, SAMP8, hereinafter referred to as mice), and water clove extract was added to the drinking water of the mice, and the memory test was carried out after 3 to 4 months ; The mice used in the experiment are short-lived and have memory loss, which is a suitable experimental animal model for Alzheimer's disease (neurodegeneration). The mouse memory experiment was first to place mice drinking 0% and 0.01% water clove extract individually in an open space box (20x20x10 inches) during the three-day training period to make the mice accustomed to the open space box; then, Two different training objects were placed in the open space box during the training period and the mice were allowed to explore the two different training objects for 5 minutes. When the memory test was performed after a period of time, the mice were ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an application of ludwigia octovalvis extract in preparing a composition for enhancing memory function and relieving neurodegeneration as well as an application of the ludwigia octovalvis extract in preparing a composition for treating alzheimer's disease. The ludwigia octovalvis extract, as an active ingredient, can be used for preparing a pharmaceutical composition for enhancing memory function and relieving neurodegeneration or a food composition for patients of alzheimer's disease.

Description

technical field [0001] The present invention relates to water clove (Ludwigia octovalvis) extract, in particular, the invention relates to the use of water clove extract for preparing a composition for enhancing memory function and delaying neurodegeneration. Background technique [0002] As the global population is aging, Alzheimer's disease has also become a problem faced by many countries. According to research estimates, more than 24 million people around the world suffer from this disease. And when the condition of Alzheimer's disease becomes more and more serious, the patient needs the help of others in all aspects of life, such as washing, eating and going to the toilet. Because people with Alzheimer's disease need people to take care of them day and night, the lives of their relatives and friends are often greatly affected. [0003] There is still no accurate diagnosis and effective treatment for Alzheimer's disease, so scientists all over the world are devoting the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P25/28
Inventor 林哲豪
Owner SUN PLAZA INT
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com