Drug-loading degradable magnetic anastomat

Abstract

The invention provides a drug-loading degradable magnetic anastomat comprising two same structure units. Each structure unit comprises an annular body and a plurality of magnets. Each annular body is composed of an inner ring and an outer ring. The magnets are evenly arrayed between the inner rings and the outer rings along the circumferential directions of the annular bodies. The inner rings can be made of degradable materials, and the outer rings can be made of mixtures of drugs for simulating healing of anastomotic stomas and the degradable materials. The drug-loading degradable magnetic anastomat formed by the annular bodies with outer layers and inner layers and the magnets arrayed along circumferences, the inner rings can be made of the degradable materials, and the outer rings can be made of the mixtures of drugs for simulating healing of anastomotic stomas and the degradable materials, so that magnetic pressure anastomosing can be realized at the initial stage of tissue cavity anastomosing; the size of the magnetic anastomat decreases gradually along with degradation of the inner rings and the outer rings, and then the magnetic anastomat can be discharged out of the body successfully; drugs released during degradation of the outer rings leak to the peripheries of the anastomotic stomas, so that wound healing is accelerated, infection risks are reduced, and anastomosing cycle is shortened.

Description

technical field [0001] The invention relates to a biodegradable anastomotic structure, in particular to a drug-loaded degradable magnetic anastomat that can promote the regeneration of anastomotic cells. Background technique [0002] For severe hepatobiliary and intestinal diseases, surgical treatment such as gallbladder, part of gastrointestinal tract, partial hepatectomy or even liver transplantation is often required. The anastomotic reconstruction technique of surgical hollow organs is a basic operation in the process of operation. Requirements for anastomotic reconstruction include: simplicity and short operation time, good serosa coaptation, few anastomotic complications, and easy excretion of the stapler after anastomosis. At present, the research on magnetic stapler has made great progress, but its structure is usually too simple, mainly including two magnetic rings, and the stapler is not easy to be discharged from the body after anastomosis. The repair of the ana...

AI Technical Summary

Problems solved by technology

At present, the research on magnetic stapler has made great progress, but its structure is usually too simple, mainly including two magnetic rings, and the stapler is not easy to be discharged from the body after anastomosis. The repair of the anastomotic stoma in the crushing process relies solely on the patient's own internal regulation. The anastomotic operation is prone to infection, and the reconstruction of the anastomotic stoma takes a long time. The biocompatibility in the body during the magnet crushing process is poor, which limits its clinical application.

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