Keggin type vacancy polyacid and application thereof in catalytic synthesis of benzoxazole derivative

A technology of benzoxazole and derivatives, which is applied in the field of preparation of inorganic functional materials, can solve the problems of unsatisfactory catalyst efficiency and product yield, difficult catalyst recovery and reuse, etc., and achieve high catalytic activity and main product selection sexual effect

Active Publication Date: 2014-03-26
BEIJING UNIV OF CHEM TECH
View PDF1 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Based on the above-mentioned rich applications of benzoxazole derivatives in the synthesis of chemical intermediates and drugs, a series of catalytic systems have been developed for the synthesis of benzoxazole derivatives, but the reported catalytic systems often have the following three Disadvantages: 1) In homogeneous reactions, c...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Keggin type vacancy polyacid and application thereof in catalytic synthesis of benzoxazole derivative
  • Keggin type vacancy polyacid and application thereof in catalytic synthesis of benzoxazole derivative
  • Keggin type vacancy polyacid and application thereof in catalytic synthesis of benzoxazole derivative

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] a. Dilute 120gNa 2 WO 4 2H 2 O was dispersed in 150ml deionized water;

[0018] B. add dropwise 6ml85wt% phosphoric acid to the solution prepared in step a;

[0019] c. Add 22ml of glacial acetic acid dropwise to the solution in step b, stir for 3 hours, filter to obtain a precipitate, and dry to obtain the Keggin type three-vacancy polyacid. Its chemical formula is Na 8 H[A-PW 9 o 34 ]·7H 2 O, where A represents the structure type of the Keggin-type three-vacancy polyacid.

[0020] Catalyzed reaction embodiment 1

[0021] The catalytic reaction is carried out in a simple glass reactor with magnetic stirring. Weigh 0.01 mmol of the Keggin-type three-vacancy polyacid prepared in Example 1 as a catalyst and disperse it in 0.2 ml of acetonitrile, then add 1 mmol of aldehyde substrate and 1 mmol of 2-aminophenol, and react at room temperature for 6 h. Extract the reaction mixture with diethyl ether, take the lower layer liquid, and filter and dry to obtain the rea...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention belongs to the technical field of application of inorganic functional materials, and discloses Keggin type vacancy polyacid and application thereof in a reaction for catalytic synthesis of a benzoxazole derivative. The chemical formula of the Keggin type trivacancy polyacid is Na8H [A-PW9O34]*7H2O, wherein A represents a structure type of the Keggin type trivacancy polyacid. The Keggin type trivacancy polyacid is taken as an environment-friendly catalyst and applied to a reaction in which aldehydes and 2-aminophenol are taken as raw materials for catalytic synthesis of the benzoxazole derivative in a liquid phase, catalysis for oximation reaction of most aldehyde or ketone under a mild condition is achieved, high catalytic activity and principal product selectivity are provided, and various problems in the conventional synthesis of the benzoxazole derivative are solved.

Description

technical field [0001] The invention belongs to the technical field of preparation of inorganic functional materials, and in particular relates to the catalytic application of a Keggin type three-vacancy polyacid in liquid phase to the synthesis of benzoxazole derivatives by using aldehydes and 2-aminophenol as raw materials. Background technique [0002] Polyacid compounds are a class of multimetal oxides containing metals such as V, Mo, W, and Nb, and these atoms are generally in their highest oxidation state. The condensation of the same oxoacid ions is called isopolyanion, and the corresponding acid is called isopolyacid. The condensation of different types of oxyacid anions is called heteropolyanion, and the corresponding acid is called heteropolyacid. They have better thermal and redox stability than common organic ligands. The redox ability, electron transfer characteristics, acidity and solubility of polyacids can be adjusted to a large extent by changing the metal...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): B01J31/18C07D263/57C07D263/56C07D413/04
Inventor 宋宇飞黄鲁江赵燊
Owner BEIJING UNIV OF CHEM TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap