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Qi-tonifying and sedative granules for acute heart failure and preparation method

A technology of acute heart failure and granules, which is applied in the field of treating acute heart failure tonifying Qi Anshen granules and its preparation, achieving the effects of low cost of medicinal materials, simple preparation methods, and convenient administration

Active Publication Date: 2014-06-18
哈尔滨美君制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Generally speaking, there is no ideal and exact traditional Chinese medicine for the treatment of acute heart failure at present.

Method used

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  • Qi-tonifying and sedative granules for acute heart failure and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Example 1 Acute heart failure Buqi Anshen granule is mainly prepared from the following raw materials, all in parts by weight (5g per part): 3 oysters, 3 poria cocos, 6 cassia twigs, 2 seabuckthorns, 6 red thistles, and Baiziren 5. Danshen 4, Mussel 5, Baibu 2, Anemarrhena 3, Astragalus 25, Alisma 4, Keel 6.

[0044] The preparation method of the above-mentioned acute heart failure Buqi Anshen granule:

[0045] (1) Mix and decoct the prepared raw medicines, and decoct three times in total, each time after the water boils, decoct for 0.5 hours, filter the juice, combine the medicine juices, evaporate with a thin film to contain 1-3 grams of crude drugs per milliliter, Add double the weight of ethanol (95%) while stirring, and filter after 8 hours of precipitation;

[0046] (2) Evaporate the filtrate with a thin film to 4 grams of crude drug per milliliter of medicinal liquid, add cold water to dilute to 1-3 grams of crude drug per milliliter, and filter after 8 hours of...

Embodiment 2

[0049] Example 2 Acute Heart Failure Buqi Anshen Granules are mainly prepared from the following raw materials, all in parts by weight (10 g per part): 9 oysters, 9 poria cocos, 10 cassia twigs, 8 seabuckthorns, 12 red thistles, and Baiziren 15, Danshen 9, Mussels 9, Baibu 5, Anemarrhena 9, Astragalus 35, Alisma 10, and Keel 10.

[0050] The preparation method of above-mentioned acute heart failure Buqi Anshen granule is:

[0051] (1) Mix the prepared raw materials and decoct the juice, and decoct three times in total. After the water is boiled, decoct for 1.2 hours each time, filter the juice, combine the medicinal juices, and evaporate with a thin film to contain 1-3 grams of crude drug per ml. Add double the weight of ethanol (95%) while stirring, and filter after 24 hours of precipitation;

[0052] (2) Evaporate the filtrate with a thin film to 5 grams of crude drug per milliliter of liquid medicine, add cold water to dilute to 1-3 grams of crude drug per milliliter, and ...

Embodiment 3

[0057] Example 3 Acute heart failure Buqi Anshen granule is mainly prepared from the following raw materials, all in parts by weight (15g each): 5 oysters, 5 poria cocos, 7 cassia twigs, 4 seabuckthorns, 8 red thistles, and Baiziren 8. Salvia 6, Mussel 6, Baibu 3, Anemarrhena 5, Astragalus 28, Alisma 6, keel 7.

[0058] The preparation method of above-mentioned acute heart failure Buqi Anshen granule is:

[0059] (1) Mix the prepared raw materials and decoct the juice, and decoct three times in total, each time after the water is boiled, then decoct for 0.7 hours, filter the juice, combine the medicinal juices, evaporate with a thin film to contain 1-3 grams of crude drug per ml, Add double the weight of ethanol (95%) while stirring, and filter after 13 hours of precipitation;

[0060] (2) Evaporate the filtrate with a thin film to 4.2 grams of crude drug per milliliter of medicinal liquid, add cold water to dilute to contain 1-3 grams of crude drug per milliliter, and filter...

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Abstract

The invention discloses Qi-tonifying and sedative granules for acute heart failure, which is prepared by the following pharmaceutical raw materials in parts by weight: 3-9 parts of oysters, 3-9 parts of poria, 6-10 parts of cassis twig, 2-8 parts of sea buckthorn, 6-12 parts of ageratum conyzoides, 5-15 parts of platycladi seed, 4-9 parts of salvia miltiorrhiza, 5-9 parts of mussel, one 2-5 parts of radix stemonae, 3-9 parts of anemarrhena asphodeloides, 25-35 parts of astragalus, 4-10 parts of alisma, and 6-10 parts of keel. The selected materials are traditional Chinese medicine materials without any toxic or side effects; the composition prescription fully complies with the Chinese medicine principles and physical and psychological characteristics of patients with acute heart failure, different compositions can be prepared according to different groups under the premise of the general principle, the functions are different, raw materials are easy to obtain, the cost of crude drugs is low, and the burden on patients can be reduced.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a granule for treating acute heart failure and a preparation method thereof. Background technique [0002] Acute heart failure (AHF) refers to the reduction of myocardial contractility and aggravation of cardiac load caused by acute attack or aggravated abnormal left ventricular function, resulting in a sudden drop in acute cardiac output, increased pulmonary circulation pressure, and increased peripheral circulatory resistance, causing pulmonary circulation. Congestion is a clinical syndrome of acute pulmonary congestion, pulmonary edema, tissue and organ hypoperfusion, and cardiogenic shock, and left heart failure is the most common. Acute heart failure can be acutely exacerbated or suddenly onset on the basis of the original chronic heart failure. Before the onset, most patients have organic cardiovascular disease, which can be manifested as systolic heart failure o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/16A61P9/04A61P9/00A61P9/10A61P11/00A61K35/02A61K35/56A61K35/618
Inventor 陈西成
Owner 哈尔滨美君制药有限公司
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