Preparation method of Chinese herbal extract, prepared Chinese herbal extract and application

A technology for extracts and traditional Chinese medicines, which is applied in the field of preparation of traditional Chinese medicine extracts, can solve the problems of unsuitable long-term storage, poor taste, waste of medicinal material resources, etc., and achieves the effects of simple and easy operation, reducing oral doses and improving compliance.

Active Publication Date: 2014-11-26
BEIJING HANDIAN PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The above method is only a simple preparation method of traditional Chinese medicine decoction, and does not consider how to fully extract the active ingredients in the medicine, which causes a serious waste of medicinal material resources, but the medicinal effect is not significant; at the same time, the water decoction brings a large dosage and poor taste , inconvenient to carry, not suitable for long-term storage

Method used

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  • Preparation method of Chinese herbal extract, prepared Chinese herbal extract and application
  • Preparation method of Chinese herbal extract, prepared Chinese herbal extract and application
  • Preparation method of Chinese herbal extract, prepared Chinese herbal extract and application

Examples

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Effect test

Embodiment 1

[0064] Example 1 A preparation method of Chinese medicine compound extract and the prepared Chinese medicine compound extract

[0065] API prescription:

[0066] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0067] The concrete steps of described preparation method are as follows:

[0068] (1) Prepare various medicinal materials according to the prescription.

[0069] (2) Add water 10 times the weight of medicinal materials to cinnamon, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 2 times the volume of absolute ethanol to dissolve the volatile oil; take 10 times the volume of the volatile oil β-cyclodextrin, an aqueous solution of β-cyclodextrin made by adding water 25 times the weight of β-cyclodextrin; at a speed of 150 rpm, slowly add volatile oil ethanol to the aqueous solution of β-cyclodextrin, Aft...

Embodiment 2

[0073] Example 2 A preparation method of Chinese medicine compound extract and the prepared Chinese medicine compound extract

[0074] API prescription:

[0075] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0076] The concrete steps of described preparation method are as follows:

[0077] (1) Prepare various medicinal materials according to the prescription.

[0078] (2) Add water 8 times the weight of the medicinal material to cinnamon, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 1 times the volume of absolute ethanol to dissolve the volatile oil, and take 6 times the volume of β of the volatile oil -Cyclodextrin, add β-cyclodextrin aqueous solution made by adding 15 times the weight of β-cyclodextrin water; at a speed of 150 rpm, slowly add volatile oil ethanol solution to the β-cyclodextrin aqueous s...

Embodiment 3

[0082] Example 3 A preparation method of Chinese medicine compound extract and the prepared Chinese medicine compound extract

[0083] API prescription:

[0084] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0085] The concrete steps of described preparation method are as follows:

[0086] (1) Prepare various medicinal materials according to the prescription.

[0087] (2) Take cinnamon, add water 12 times the weight of the medicinal material, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 3 times the volume of absolute ethanol to dissolve the volatile oil, and take 20 times the volume of the volatile oil β-cyclodextrin, β-cyclodextrin aqueous solution made by adding water 40 times the weight of β-cyclodextrin; at a speed of 150 rpm, slowly add volatile oil ethanol solution to the β-cyclodextrin aqueous solu...

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Abstract

The invention provides a preparation method of a Chinese herbal extract and the prepared Chinese herbal extract. Active pharmaceutical ingredients of the Chinese herbal extract comprise, by weight, 30-60 parts of Radix Astragali, 9-15 parts of ligustrum lucidum, 9-30 parts of motherwort, 3-10 parts of dark plum, 2-9 parts of coptis, 1-5 parts of cortex cinnamomi and 3-9 parts of Buddleja officinalis. The preparation method comprises the following steps: extracting volatile oil from cortex cinnamomi, and carrying out clathration on the volatile oil with beta-cyclodextrin; extracting cortex cinnamomi herbal residue and other medicinal materials with 30%-80% (by volume) of an ethanol solution; and refining an extract by passing through macroporous resin and drying to obtain a dry extract powder, adding a volatile oil clathrate, and uniformly mixing. By the preparation method, active material content and pharmacological action of the Chinese herbal extract are boosted remarkably.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a preparation method of a traditional Chinese medicine extract for diabetic retinopathy, the prepared traditional Chinese medicine extract and its application. Background technique [0002] Diabetic Retinopathy (DR) is one of the serious and common eye complications of diabetes. With the prolongation of the duration of diabetes, the incidence of DR also increased. The incidence of diabetic retinopathy is about 50% in those with a course of more than 8 years. The early symptoms of the disease are not obvious and are easy to be ignored. In the late stage, there is no effective control method, and the disease is lingering and intractable. If the disease is not treated, the consequences are serious, and it is the main cause of adult blindness, with a blinding rate of 8-12%, which has a serious adverse effect on the quality of life of the affected population. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P27/02A61P9/10A61P3/10
Inventor 林德良
Owner BEIJING HANDIAN PHARMA CO LTD
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