The present invention belongs to the technical field of Chinese
medicine preparations, and specifically relates to a Qifuyin compound granule, a preparation method and a
quality control method thereof. The granule is composed of seven medicines, namely,
ginseng,
Rehmannia glutinosa, Chinese angelica, stir-fried
Atractylodes macrocephala, roasted licorice, Chinese date seeds and processed
Polygala tenuifolia; the preparation method of the granule is mainly to adopt different
extraction methods for different raw materials, to enclose volatile oil with β-
cyclodextrin, to concentrate the filtrate extracted by classification, to add
inclusion compound and auxiliary materials, to mix and granulate to obtain the finished product; the present invention optimizes and screens the preparation process parameters of the granule, and also performs
thin layer identification on
ginseng,
Rehmannia glutinosa, roasted licorice, Chinese angelica and processed
Polygala tenuifolia in the
quality control method, and performs quantitative detection on ginsenosides and 3,6′-dierucyl
sucrose. Compared with traditional decoctions, the granules prepared by the present invention retain the effective ingredients such as volatile oils and ginsenosides to the maximum extent, improve the
efficacy, save Chinese
medicine resources, standardize the quality standards, and are suitable for industrial production.