32results about How to "To achieve the purpose of reducing toxicity and increasing efficiency" patented technology

The invention discloses a method for preparing siwu decoction formula granules and a quality control method thereof. The method for preparing the siwu decoction formula granules comprises steps: prepared rehmannia roots, angelica sinensis, radix paeoniae alba and ligusticum wallichii medicinal slices are added with water which is 5-15 times of the weight of total inventory, are extracted for two times, aromatic water is collected and is combined with two frying filter liquids, are decompressed and concentrated in vacuum, a concentrated solution is added with beta (Beta)-cyclodextrin and silicon dioxide to uniformly stir and obtains a clear paste, and the aromatic water and the aromatic water are sprayed and dried after being uniformly mixed, and are pelletized through a dry method to prepare the siwu decoction formula granules. The quality control method of the siwu decoction formula granules comprises qualitative identification of an infrared fingerprint spectrum and a thin layer and content determination of a high performance liquid chromatography (HPLC). The method for preparing siwu decoction formula granules and the quality control method thereof decoct in a combined mode according to a traditional method, can perfectly take full advantages of drug matching compared with an existing method that various medicinal odours are added when single formula particles are taken, reflects the overall concept of Chinese medicine, guarantees to achieve the purpose of reducing toxicity and enhancing efficacy, supplies novel selection for clinical medication, builds a perfect quality standard, controls quality by combining a power-spectral method and a chromatography, and can effectively control quality of complex granules from the overall to the more specific.

The invention relates to a preparation and preparation method of ginseng flower. Honey, onion and ginseng flower are scientifically processed into a preparation, which retains the active ingredients of ginseng flower, enhances the effect of ginseng flower for nourishing qi, and changes the coldness of ginseng flower. Coolness, after adding refined honey, it can increase the moistness of ginseng, reconcile the medicinal properties of the present invention, improve the taste and be more conducive to human body absorption, and improve the tonic effect of ginseng. At the same dose, the purpose of reducing toxicity and increasing efficiency can be achieved. It is of great significance to protect scarce medicinal resources.

The invention discloses a preparation method and a quality control method of rhizoma cyperi four-material granules. The preparation method comprises the steps of extracting volatile oil from four medicinal materials including angelica, Szechuan lovage rhizome, rhizoma cyperi and costus root by adopting a steam distillation method, performing grinding inclusion on the volatile oil by adopting beta-cyclodextrin, adding prepared rehmannia root, white peony root and rhizoma corydalis into the residue obtained after the volatile oil is extracted, adding water for decocting and extracting, precipitating the extract by using 95% ethanol, standing, filtering, concentrating the supernate under reduced pressure, drying to obtain a dry extract, adding powdered sugar and dextrin, mixing uniformly, granulating, drying, shaping, adding an inclusion compound, and mixing uniformly, thus obtaining the four-material granules. The quality control method comprises thin-layer qualitative identification and HPLC (High Performance Liquid Chromatography) content measurement. The volatile oil is separately extracted and included, so that double effects of reducing the consumption of accessories and exerting the treatment effect are achieved; compared with the conventional single-formula granules, the four-material granules having various medicinal flavors can sufficiently exert the advantage of compatibility of Chinese medicaments; and a perfect quality standard is established, so that the quality of the compound granules can be effectively controlled.

The invention discloses a preparation method of pubescent angelica and mistletoe decoction formula granules and a quality control method thereof. The preparation method includes the steps that radix angelicae pubescentis, asarum, cassia twigs, radices sileris, ligusticum wallichii and radix angelica sinensis are extracted for obtaining volatile oil, and the volatile oil is subjected to clathration of beta-cyclodextrin; water with the weight 5-15 times the weight of total feeding amount is added to herbal residues and other nine types of medicine, and decoction and extraction are conducted twice; filtrate is subjected to vacuum decompression concentration; a concentrated solution is subjected to spray drying, spray-drying powder is obtained, and the spray-drying powder is crushed into submicron powder through an airflow pulverizer; maltodextrin and a beta-cyclodextrin clathrate compound are added to the submicron powder to be mixed uniformly, granulation is conducted through a dry method, and the pubescent angelica and mistletoe decoction formula granules are obtained. The quality control method includes the steps of infrared fingerprint spectra, thin-layer qualitative identification and HPLC content measuring. By means of the method, the advantage of drug matching can be fully played, and effective ingredients are maintained to the maximum degree; a perfect quality standard is completed, a once-measurement multi-evaluation technology of thin-layer chromatography is adopted, quality control is conducted in combination with infrared spectroscopy and chromatography, and the quality of the formula granules can be effectively controlled.