A kind of double rattan microemulsion gel and preparation method thereof
A technology of microemulsion gel and gel matrix, which is applied in the field of medicine, can solve the problems of large side effects, strong toxicity, and low utilization, and achieve the effects of quick onset of action, reduced toxicity, and reduced dosage
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0052] Embodiment 1 Double rattan microemulsion gel formula research
[0053] 1. The method of drawing the pseudo-ternary phase diagram of microemulsion is as follows:
[0054] S1. The surfactant (AEO-9 / OP emulsifier 8:2) and co-surfactant (absolute ethanol) according to the Km value (the ratio of surfactant to co-surfactant) is 3:1, 3: 2. Mix 2:1, 1:1, 1:2, 2:3, and 1:3 separately, and mix evenly on a magnetic stirrer;
[0055] S2. According to the ratio of 9:1, 8:2, 7:3, 6:4, 5:5, 4:6, 3:7, 2:8, 1:9, add to the mixture (Smix) obtained in S1 Oil phase (oleic acid), mix well;
[0056] S3. Place on a magnetic stirrer to adjust the temperature and rotating speed, add the water phase to the mixture drop by drop; observe the critical point when the mixed solution changes from clear to turbid, and from turbid to clear, and record the critical addition amount.
[0057] S4. Use Origin7.0 software to draw a pseudo-ternary phase diagram, and determine the proportion of each phase co...
Embodiment 2
[0147] Example 2 Preparation method of Shuangteng microemulsion gel
[0148] At room temperature, take 1.5g of the extracts of C. chinensis and Tripterygium wilfordii (ratio 1:1), add them to 1.58g of oleic acid for ultrasonic dissolution, add 7.58g of AEO-9, 1.89g of OP emulsifier, 4.73g of absolute ethanol, Stir ultrasonically evenly, add 80.72g of water drop by drop under the action of a magnetic stirrer to obtain Shuangteng microemulsion; add 2g Cp-940 to Shuangteng microemulsion, swell for 24 hours, adjust pH to 6~7, and stir evenly to obtain Shuangteng microemulsion. Rattan Microemulsion Gel.
[0149] The obtained Shuangteng microemulsion gel is composed of the following components in mass ratio: S. chinensis extract and Tripterygium twig extract 1.5%, oleic acid 1.58%, AEO-9 7.58%, OP emulsifier 1.89%, anhydrous 4.73% ethanol, 2% Cp-940, and the balance is water; the extract of C. chinensis: Tripterygium wilfordii extract=1:1.
Embodiment 3
[0150] The preparation method of embodiment 3 double rattan microemulsion gel
[0151] At room temperature, take 1 g of the extracts of Teng Teng Teng and Tripterygium wilfordii (ratio 1:1), add them to 1.47 g of oleic acid for ultrasonic dissolution, add 7.63 g of AEO-9, 1.72 g of OP emulsifier, and 5.23 g of absolute ethanol, and ultrasonically Stir evenly, add 80.95g of water drop by drop under the action of magnetic stirring to obtain Shuangteng microemulsion; add 2g Cp-940 to Shuangteng microemulsion, swell for 24 hours, adjust pH to 6~7, and stir evenly to obtain Shuangteng microemulsion glue.
[0152] The obtained Shuangteng microemulsion gel is composed of the following components in mass ratio: S. chinensis extract and Tripterygium twig extract 1%, oleic acid 1.47%, AEO-9 7.63%, OP emulsifier 1.72%, anhydrous 5.23% ethanol, 2% Cp-940, and the balance is water; the extract of C. chinensis: Tripterygium wilfordii extract=1:1.
PUM
Property | Measurement | Unit |
---|---|---|
particle size | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com