Warm light drink compound formula granule, as well as preparation method as well as detection method thereof

A technology for formula granules and compound recipes, which is applied in the field of Wenqingyin compound formula granules and their preparation, can solve problems such as drug effect effects, and achieve the effects of promoting modernization and facilitating drug storage.

Inactive Publication Date: 2013-05-08
KANGMEI PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, single-flavored traditional Chinese medicine formula granules, directly ingested, have a certain impact on its efficacy.

Method used

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  • Warm light drink compound formula granule, as well as preparation method as well as detection method thereof
  • Warm light drink compound formula granule, as well as preparation method as well as detection method thereof
  • Warm light drink compound formula granule, as well as preparation method as well as detection method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] The invention provides a Wenqingyin compound formula granule, which comprises powdered volatile oils of angelica and chuanxiong, and dry extract powder of angelica, chuanxiong, scutellaria baicalensis, rehmannia glutinosa, berberine, cortex phellodendri, gardenia and peony root.

[0050] Among them, the prescription of the granule is: Angelica 4.5g, Scutellaria baicalensis 4.5g, Rehmannia glutinosa 4.5g, Rhizoma Chuanxiong 4.5g, Coptis chinensis 4.5g, Cortex Phellodendron 4.5g, Gardenia 4.5g, Paeoniae Alba 4.5g.

Embodiment 2

[0052] The preparation method of Wenqingyin compound formula granules:

[0053] a) Preparation of volatile oil of Angelica sinensis and Rhizoma Chuanxiong: take 4.5g of Angelica sinensis and 4.5g of Rhizoma Chuanxiong, steam distill for 3 hours to extract volatile oil, collect the volatile oil in another device and use cyclodextrin saturation technology to make volatile oil clathrate, take and collect The volatile oil, measure the volume, add 2 times the volume of ethanol to dilute; then take 10 times the volume of β-cyclodextrin of the volatile oil, add 1.5 times the volume of water to grind for 10 minutes, add the volatile oil ethanol diluent, grind together for 30 minutes, place , after drying, the clathrate was dried under reduced pressure at 40°C for 24 hours, taken out, ground into fine powder, and set aside. Conducive to preservation.

[0054] b) Preparation of dry extract powder of Scutellaria baicalensis, Rehmannia glutinosa, Coptis chinensis, Cortex Phellodendron, G...

Embodiment 3

[0058] Process optimization and screening of the preparation method of Wenqingyin compound formula granules:

[0059] 1) Selection of influencing factors of water extraction process

[0060] Weigh 1 / 10 of the prescription amount of medicinal materials for water extraction, add water equivalent to 10 times the weight of the added medicinal materials, and decoct 3 times, each decocting for 1 hour to obtain an extract. The extract yield, baicalin and geniposide content of the first, second and third decoction were determined respectively. The results are shown in Table 1.

[0061] Table 1 Selection of decoction times

[0062]

[0063] The above experimental results show that, taking the yield of the extract as the index, the third water extraction accounts for 8.7% of the extract; taking baicalin and geniposide as the investigation indicators, it has decreased, indicating that the two water extractions have basically extracted completely, so the process of water extraction ...

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Abstract

The invention provides a warm light drink compound formula granule comprising angelica sinensis extract, ligusticum wallichii extract, scutellaria baicalensis extract, prepared rehmannia root extract, coptis chinensis extract, golden cypress extract, gardenia extract and radix paeoniae alba extract, wherein the mass ratio of the raw herbal materials of the above components is 1:1:1:1:1:1; the invention further provides a preparation method and a detection method of the above light drink compound formula granule. By adopting the formula granule, the preparation method and the detection method, the shortage caused by the simple addition of each medicine when the existing unit formula granule is taken is overcome, the technical condition and the complete quality standard of the light drink compound formula granule are created, the quality of the formula granule can be effectively controlled, and the medicine is convenient to store and carry by a user.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to Wenqingyin compound formula granules, a preparation method and a detection method thereof. Background technique [0002] Wenqing Yinyao Fang comes from Volume 6 of "Wanbinghuichun", which was written by Gong Tingxian, the "Medical Champion" of the Ming Dynasty. Can't stop, or like bean juice, with mixed colors, pale complexion, tingling pain in navel and abdomen, alternate cold and heat, metrorrhagia and metrorrhagia. This prescription is actually composed of Siwu Decoction and Huanglian Jiedu Decoction. It has the functions of nourishing blood and fire, regulating camp and detoxification. Ulcers, improve immunity, anti-inflammatory analgesic, antipyretic, sedative, hemostatic and other effects. It has been applied to skin diseases caused by accumulation of blood heat, dermatomyositis, recurrent aphtha, lupus erythematosus and other diseases. [0003] T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/16A61P15/00A61P7/04A61P17/00A61P21/00A61P1/02A61P37/02A61P19/04A61P37/04A61P29/00A61P25/20G01N30/02G01N30/90
Inventor 李亚军向飞军许冬瑾马兴田汪涛孙亮
Owner KANGMEI PHARMA
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