35results about How to "Low CMC value" patented technology

The present invention relates to a kind of hydrolysis-resistant Si-C-Si type cationic organosilicon surfactant, it passes chloropropyl silane and N-methylimidazole, N-methylpyrrolidine, N,N-dimethylethanolamine , Trimethylamine, triethylamine or pyridine and other reactions. The surfactant prepared by the invention has excellent surface activity and certain bactericidal properties, and can be used in the fields of pesticide auxiliaries, drug sustained release, functional nanometer materials, textile processing aids and the like.

The invention discloses a hypoxia-responsive polyamino acid-PEG stereotactic drug-loaded micelle and a preparation method thereof. The preferred method is to obtain 2,2-bis [(2‑nitro‑1H‑imidazol‑1‑yl)methyl]‑1,3‑propanediol, and then acid halide with p-nitrobenzoyl chloride in the presence of triethylamine to obtain 2,2‑bis[( 2‑nitro‑1H‑imidazol‑1‑yl)methyl]propane‑1,3‑diylbis(4‑nitrophenyl) carbonate, and paclitaxel in N,N‑diisopropylethylamine Catalyzed reaction, then add poly L-amino acid-PEG or poly D-amino acid-PEG, respectively to obtain double 2-nitroimidazole-paclitaxel-poly L-amino acid-PEG, and double 2-nitroimidazole-paclitaxel-poly D Amino acid-PEG, the last two are mixed in equal amounts in PBS buffer, homogenized at high speed, and extruded through a filter membrane with a pore size of 100nm. The drug-loaded micelles prepared by the invention have high encapsulation efficiency and low-oxygen response characteristics, can effectively accumulate in tumor tissues to achieve good anti-tumor effects, and reduce drug distribution in other normal tissues to reduce toxic and side effects.

The invention relates to a novel dimeric cationic surfactant. The structural formula of the surfactant is indicated as formula (A). The dimeric cationic surfactant introduces groups at a polar head to reach chemical bonding, restrain separating force among the original single-chain single heads and improve appetency among carbon chains, thereby improving surface activity and opening a brand new pathway for practical application. The surfactant has good water solubility. Compared with the general single-head surfactant, the surfactant has low surface tension and a cmc value and is a novel surfactant with a wide application prospect. As shown in the specification, wherein, n=18, 16, 14 or 12.

The invention relates to a bacterium S2 for efficiently generating biosurfactant and a fermentation culture medium thereof, belonging to the field of biotechnology. The bacterium S2 is gram-negative bacterium which is rod-shaped, is (6-8)*(8-12) micrometers in size and has no spores and capsules. The bacterial strain belongs to the pseudomonas aeruginosa through identifying by morphological and physio-biochemical characteristics and molecular biology, and the collection code is CGMCC No.3034. The best fermentation culture medium is a novel culture medium which takes 50g / L of rapeseed oil as the only carbon source. The rhamnolipid is the only fermentation product of the bacterial strain and has high yield. The CMC (Critical Micelle Concentration) value of the fermentation liquid is 0.25 g / L; compared with the common chemical surfactant, the bacterium has more obvious emulsification and durability on hydrophobic substances, such as oils and the like.

The invention relates to a pesticide adjuvant, in particular to a wetting agent for pesticide preparations, a method for preparing the wetting agent and application of the wetting agent to the pesticide preparations. The method for preparing the wetting agent for the pesticide preparations includes steps of adding salicylic acid and potassium hydroxide into a reactor, then adding triethylene tetramine into the reactor drop by drop to obtain intermediate monoamide, adding dehydroabietic acid into the reactor and carrying out a series of reaction to obtain intermediate asymmetric bisamides; adding the intermediate asymmetric bisamides and butanone into the reactor, adding propane suhone into the reactor drop by drop, carrying out suction filtration, repeatedly washing substances in the reactor by the aid of butanone, re-crystallizing the substances, neutralizing the substances by the aid of ethanol solution of alkali, separating white solid from the substances, carrying out suction filtration and drying the white solid under the vacuum condition to obtain the wetting agent for the pesticide preparations. The wetting agent, the method and the application have the advantages that the wetting agent for the pesticide preparations is of an asymmetric structure with the bisamides and bis-sulfonate and is excellent in surface activity, compound property and wetting property, and the pesticide absorption rate can be increased.

The invention relates to a preparation method of a chitosan-based cationic gemini asphalt emulsifier. The emulsifier is prepared by reacting chitosan / O-carboxylated chitosan with ethylene glycol diglycidyl ether. The outstanding feature of the invention is that rich biomass chitosan is selected as the reaction raw material and water is used as the reaction solvent, which not only reduces the production cost of the emulsifier, but also meets the requirements of green raw materials. The Gemini-type asphalt emulsifier prepared by the present invention has higher surface activity and lower CMC value than traditional emulsifiers, and can emulsify various types of asphalt. The prepared asphalt emulsion is fine and uniform, and has higher storage life. Stability, all performance indicators have reached the technical requirements of emulsified asphalt for roads in JTG F40-2004, the technical specification for highway asphalt pavement construction.

The invention provides a high foam-stabilizing, low-sensitivity concrete air-entraining agent and a preparation method, belonging to the technical field of concrete admixture preparation. ~40%, viscosity regulator 2~4%, foam stabilizer 2~8%, synergist 1~3%, water 45~75%; Gemini surfactant and various functional components act synergistically to significantly improve foaming and foam stabilization capabilities. Compared with conventional air-entraining agents, it has the advantages of low dosage, high foam stabilization, and high adaptability to hard water, which can meet the requirements of high and cold conditions. Requirements for use in harsh environments such as low pressure.

The invention relates to a preparation method of 1,1'-dialkyl-3,3'-(2-phosphate-1,3-propylene) imidazole inner salt compound. The 1,1'-dialkyl) 3,3'-(2-phosphate-1,3-propylene) imidazole inner salt compound of the present invention is an amphoteric gemini surfactant, and the specific synthesis method includes 1, Synthesis of 3-dichloro-2-propanol, synthesis of N-alkylimidazole, 1,1'-dialkyl-3,3'-(2-hydroxy-1,3-propylene)imidazole hydrochloride The synthesis of the salt and the synthesis of the 1,1'-dialkyl-3,3'-(2-phosphate-1,3-propylene) imidazole inner salt are four steps. The 1,1'-dialkyl-3,3'-(2-phosphate-1,3-propylene) imidazolium internal salt of the present invention and the preparation method thereof have easy-to-obtain raw materials, easy-to-control reaction process conditions, and easy operation. Simple, the product is easy to purify, and the yield is high. The substance has a low critical micelle concentration and is useful as a wetting agent, emulsifier, foaming and foam stabilizer. The macrocyclic imidazole head group and phosphate group in the molecular structure make it have good thermal stability, solubility, salt resistance, temperature resistance and acid and alkali resistance.