Preparation method and quality control method of rhizoma cyperi four-material granules

Abstract

The invention discloses a preparation method and a quality control method of rhizoma cyperi four-material granules. The preparation method comprises the steps of extracting volatile oil from four medicinal materials including angelica, Szechuan lovage rhizome, rhizoma cyperi and costus root by adopting a steam distillation method, performing grinding inclusion on the volatile oil by adopting beta-cyclodextrin, adding prepared rehmannia root, white peony root and rhizoma corydalis into the residue obtained after the volatile oil is extracted, adding water for decocting and extracting, precipitating the extract by using 95% ethanol, standing, filtering, concentrating the supernate under reduced pressure, drying to obtain a dry extract, adding powdered sugar and dextrin, mixing uniformly, granulating, drying, shaping, adding an inclusion compound, and mixing uniformly, thus obtaining the four-material granules. The quality control method comprises thin-layer qualitative identification and HPLC (High Performance Liquid Chromatography) content measurement. The volatile oil is separately extracted and included, so that double effects of reducing the consumption of accessories and exerting the treatment effect are achieved; compared with the conventional single-formula granules, the four-material granules having various medicinal flavors can sufficiently exert the advantage of compatibility of Chinese medicaments; and a perfect quality standard is established, so that the quality of the compound granules can be effectively controlled.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine formula granules, and in particular relates to a preparation method of Xiangfu Siwu granules and a quality control method thereof. Background technique [0002] Xiangfu Siwu Decoction is composed of seven herbs such as Cyperi cyperi, Muxiang, Corydalis Corydalis, Angelica, Chuanxiong, Rehmannia glutinosa, and Paeoniae Alba. It is one of the representative prescriptions for promoting qi and removing blood stasis. It has the effects of nourishing blood and regulating blood, promoting qi and relieving pain, and mainly treating dysmenorrhea and irregular menstruation caused by qi stagnation and blood stasis. [0003] The occurrence of dysmenorrhea is mainly related to the increase in the synthesis and release of prostaglandins in the endometrium during menstruation, the hyperreactivity of the uterine muscle, and the secondary ischemia of the myometrium leads to pain. Traditional ...

AI Technical Summary

Problems solved by technology

However, due to the disadvantages of deployment, carrying, temporary decoction, and long-term storage, it is prone to mildew and deterioration, the soup tastes bitter, and the quantity is large. It cannot meet the living requirements of modern people.

Traditional Chinese medicine formula granules maintain the multiple effects of single medicines, and retain the active ingredients of medicines to the greatest extent. However, at present, traditional Chinese medicine formula granules are all single Chinese medicine extracts. The difference between "co-frying" and "separate frying"

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