57results about How to "Hypoglycemic effect" patented technology

The invention discloses health-care rice suitable for diabetics and a processing method thereof, which belongs to the field of grain processing and can be popularized and applied in the fields of grain industry, food industry and health-care products. The health-care rice contains the following raw materials in percentage by mass: 40 to 55 percent of husked rice, 15 to 25 percent of millet, 10 to 20 percent of pearl barley, 8 to 12 percent of buckwheat, 5 to 10 percent of avena nuda, 3 to 6 percent of yam flour, 0.2 to 3 percent of kudzuvine root powder, 0.3 to 0.8 percent of taurine, 0.5 to 1.5 percent of konjac fine flour and 0.8 to 1.5 percent of sodium alginate. The processing method comprises the following steps of: crushing the husked rice, the millet, the pearl barley, the buckwheat and the avena nuda into powder of 60 to 120 meshes, proportioning the crushed raw materials and the yam flour, the kudzuvine root powder, the taurine, the konjac fine flour and the sodium alginate according to a formula proportion, mixing uniformly, adding water in an amount which is 20 to 28 percent of the mass of the total raw materials, fully stirring, putting the mixture in an extruder, extruding the mixture into strips, preparing the strips into rice grains by using a rice grain forming machine, and drying and packing. The health-care rice has balanced nutrition, can be eaten for a long term, has the effect of stabilizing and even reducing the blood sugar, has obvious effect of preventing and relieving the diabetes, and is suitable to be eaten by the diabetics.

The invention relates to a method for preparing pine needle distilled and concentrated solution. The pine needle distilled and concentrated solution can serve as medicaments and food and has obvious effect on people with hyperglycemia. The method comprises the following steps of: selecting red pine needles for performing preprocessing; performing distillation, condensation and oil-water separation on the preprocessed pine needles; performing secondary distillation and oil-water separation again; combining supernatants obtained by twice extraction; placing the obtained distilled supernatants in a shade for 10 to 40 days; ripening the supernatants to obtain softgel capsules or oral solution; and packaging to obtain the finished products. The pine needle distilled and concentrated solution can effectively help patients with the hyperglycemia maintain healthy blood sugar and has a total effective rate of treatment effects up to 87 percent according to experiments. The pine needle distilled and concentrated solution has the advantages of purely natural botanical extract products, simple extraction method, small equipment investment, readily available raw material, rich resources, economy and low price, and obvious effects on people with the hyperglycemia and development and application values.

The invention provides an oral nanometer insulin micelle preparation, comprising a therapeutically effective amount of insulin, pegylated phosphatide and pharmaceutically acceptable adjuvant. The insulin micelle preparation is prepared by using a one-step self-assembly method; particles with a uniform size can be formed, and the entrapment rate of insulin reaches more than 99.0%. In the micelle preparation, polyethylene glycol long chains can be distributed on the surface of a hydrophobic nucleus of an entrapment drug to form a hydrophilic protection film, which is favorable for overcoming a slime layer barrier, an enzyme barrier and an epidermal barrier in an alimentary canal system and protecting smooth entering of insulin into a blood circulation system for performance of hypoglycemic activity.

The invention discloses fruit-vegetable milk powder. The fruit-vegetable milk powder comprises, by weight percent, 20-80% of milk powder, 5-70% of fruit-vegetable powder, and 5-20% of sugar. The fruit-vegetable powder comprises, by weight percent, 5-50% of carrot, 5-40% of pumpkin, 10-60% of potato, and 5-40% of apple. The fruit-vegetable powder is made by soaking fresh vegetables in sterilizing water for more than 30 minutes, drying and dewatering at 60-100 DEG C, and pulverizing and screening under the fineness of more than 150 meshes. The dried and dewatered fruit-vegetable powder can be mixed well with the milk powder and the sugar before packaging.

An active largehead atractylodes saccharide complex is produced through water soaking largehead atractylodes rhizome, organic solvent precipitating, water dissolving the precipitate, dialyzing or membrane separating the supernatant liquid, concentration and drying to obtain coarse product, column chromatographic separation of the coarse product to obtain fine largehead atractylodes saccharide compound. The process is simple and high in yield and is suitable for industrial production. The largehead atractylodes saccharide complex contains polysaccharide in 40-60 wt%, alduronic acid in 15-45 wt% and protein in 10-25 wt% and the polysaccharide includes glucose, galactose, mannose, arabinose and rhamnose. The largehead atractylodes saccharide complex has obvious blood sugar reducing effect and no toxic side effect.

The invention relates to an application of a medicinal salt or a derivative of heparin and low molecular heparin for preparing an oral medicament composition, belonging to the field of medicines. The oral medicament composition enables a diabetic to recover after long-time treatment of diabetes, can prevent a patient who has reduced sugar tolerance from becoming a diabetic and can improve the vitality of islet cell beta. The medicinal application of the medicinal salt or the derivative of the heparin and the low molecular heparin has significant treatment effect and is quite suitable for clinical application.

The invention provides a preparation method of traditional Chinese medicine granules, and the traditional Chinese medicine granules prepared by the same. The traditional Chinese medicine granules comprise the following crude drugs in parts by weight: 30-60 parts of astragalus membranaceus, 9-15 parts of glossy privet fruit, 9-30 parts of motherwort, 3-10 parts of smoked plum, 2-9 parts of coptis chinensis, 1-5 parts of cinnamon and 3-9 parts of butterflybush flower. The preparation method comprises the following steps: extracting essential oil from cinnamon, and covering the essential oil by beta-cyclodextrin; extracting astragalus membranaceus, glossy privet fruit and butterflybush flower by use of an ethanol solution I; extracting residues of the smoked plum and the cinnamon, and residues of the astragalus membranaceus, the glossy privet fruit and the butterflybush flower by water; extracting the motherwort and the coptis chinensis by use of an ethanol solution II; mixing each part of extracted extractum; adding pharmaceutical acceptable auxiliary materials, pelletizing, and adding an essential oil inclusion compound; and evenly mixing the materials, so as to obtain the traditional Chinese medicine granules. Compared with the prior art, the preparation method has the advantage of obviously improving the active substance content and pharmacologic action of the traditional Chinese medicine granules.

The present invention provides a black root Korean ginseng and its preparation process. The black root Korean ginseng has saponin content obviously higher than other red ginseng products. The preparation process of the black root Korean ginseng includes adding astragalus root 20%, root of straight ladybell 20%, acanthopanax bark 20%, ophiopogon root 17%, tuckahoe 16% and dry ginger 7% into solvent; heating and concentrating to obtain concentrated solution; soaking red ginseng in the concentrated solution, and repeated steaming and drying for nine times.

The invention provides a traditional Chinese medicine capsule for treating diabetic retinopathy and an application of the traditional Chinese medicine capsule for treating diabetic retinopathy. The traditional Chinese medicine comprises the following raw materials in parts by weight: 30 to 60 parts of astragalus membranaceus, 9 to 15 parts of glossy privet fruit, 9 to 30 parts of leonurus, 3 to 10 parts of smoked plum, 2 to 9 parts of coptis chinensis, 1 to 5 parts of cortex cinnamomi and 3 to 9 parts of butterflybush flower. The preparation method of the capsule comprises the following steps: extracting a volatile oil from the cortex cinnamomi and enveloping the volatile oil with Beta-cyclodextrin; extracting medicinal residues of the cortex cinnamomi and the rest of medicinal materials by virtue of an ethanol solution with the volume percentage concentration of 30% to 80%; refining an extract with macroporous adsorption resin and drying so as to obtain dry extract powder; adding a volatile oil clathrate into the dry extract powder, evenly mixing, adding pharmaceutically acceptable auxiliary materials and filling into a capsule so as to obtain the traditional Chinese medicine capsule. Compared with the prior art, the content of active substances in the traditional Chinese medicine capsule provided by the invention is obviously improved, so that the obvious pharmacologic action of the traditional Chinese medicine capsule provided by the invention is achieved.

The invention relates to a traditional Chinese medicine composition containing dendrobium huoshanense and having a hypoglycemic effect, and a preparation method thereof. The traditional Chinese medicine composition is composed of Chinese medicinal plant dendrobium huoshanense, ginseng, boxthorn fruit and fructus momordicae, which are compounded together at set weight part ratio. The preparation method comprises the following steps: selecting the Chinese medicinal plant dendrobium huoshanense, ginseng, boxthorn fruit and fructus momordicae according to the set weight part ratio, and mixing and adding resolvent ethanol to prepare a mixed solution; obtaining an extract with an officinal value in the mixed solution through a backflow extraction method; filtering out medicine slag; processing the extract to obtain the traditional Chinese medicine composition provided by the invention; and adding auxiliary medicinal materials to prepare Chinese herbal preparation having the hypoglycemic effect.

The present invention relates to biomedicine technology, and is especially one kind of pant extract with blood sugar lowering activity and its application. The preparation process includes reflux extraction of yacon leaf in water solution of methanol, ethanol or acetone, and recovery of solvent; or decoction of yacon leaf in water to obtain the pant extract with blood sugar lowering activity. The present invention has the advantages of high bioavailability, obvious blood sugar lowering effect, no toxic side effect, etc.

The invention relates to a composition of traditional Chinese medicine extracts for treating diabetes, which is a composition of extracts of scutellaria, coptis and astragalus, in particular extracts of 20 to 40 percent of scutellaria total flavone, 30 to 50 percent of coptis total alkaloids and 20 to 40 percent of astragalus total polysaccharide by weight percentage, preferably ratio of the extracts being 40 percent to 40 percent to 20 percent, 25 percent to 50 percent to 25 percent, and 1 to 1 to 1. Baicalin is used as a standard, the content of the scutellaria total flavone measured by a UV method is 80 to 89 percent, and the content of the baicalin measured by an HPLC method is 15 to 23 percent. Berberine hydrochloride is used as a reference substance, the content of the coptis total alkaloids measured by the UV method is 70 to 90 percent, and the content sum of jateorhizine, palmatine and berberine measured by the HPLC method is 50 to 68 percent. Anhydrous dextrose is used as a standard, and the content of the astragalus total polysaccharide measured by a UV phenol-sulphuric acid method is 30 to 60 percent.

A tablet composition containing N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine and a disintegrator selected from the group consisting of sodium carboxymethyl cellulose, calcium carboxymethyl cellulose and croscarmellose sodium is disclosed. This tablet composition is rapidly disintegrated in the stomach after the administration and absorbed without being influenced by meals to inhibit the rise of the blood sugar levels of diabetics after meals.

The invention discloses a health care product for reducing blood glucose and blood fat and a preparation method of the health care product. The health care product comprises 290-300 parts of onion freeze-dried powder, 82-88 parts of bitter melon extracts, 20-28 parts of ginkgo leaf extracts, 90-96 parts of mulberry leaf extracts and 4-7 parts of magnesium stearate. The preparation method of the health care product includes the steps: firstly, crushing the onion freeze-dried powder, the bitter melon extracts, the ginkgo leaf extracts and the mulberry leaf extracts, and sieving crushed materialsby a screen with 80-100 meshes to obtain fine raw material powder; secondly, mixing the fine raw material powder for 20-30 min, humidifying the mixed raw material powder to obtain mixed materials, and sieving the mixed materials by a 20-mesh screen to obtain wet particles; thirdly, performing boiling and drying on the wet particles, adding the magnesium stearate, uniformly mixing mixture, sievingthe mixture by a 18-mesh screen to obtain dry particles, and performing filling with the dry particles to form capsules to obtain the health care product for reducing the blood glucose and the bloodfat. The acquired health care product can remarkably improve health conditions of diabetes mellitus and high-blood-fat people and can also prevent diabetes mellitus and high-blood-fat diseases for common people.

The invention provides a bitter gourd peptide composition for preventing and treating diabetes and a preparation method thereof. The bitter gourd peptide composition for preventing and treating diabetes is prepared from the following raw materials in parts by weight: 10-15 parts of a bitter gourd extract, 20-25 parts of a radix puerariae extract, 10-15 parts of a folium mori extract, 10-15 parts of a lily bulb extract, 10-15 parts of a rhizoma dioscoreae extract, 10-15 parts of a Chinese wolfberry extract, 5-10 parts of a honeysuckle flower extract, 15-20 parts of collagen peptide, 2-3 parts of a white kidney bean extract, 10-15 parts of isomaltooligosacharide, 3-5 parts of fructo-oligosaccharide, and 1-2 parts of grosvenor momordica fruits. Functional active substances are extracted and enriched from medicinal and edible traditional Chinese medicinal materials, pancreatic cell activity is enhanced, insulin secretion is stimulated, alpha-amylase activity is inhibited, digestive absorption of starch and other carbohydrates in foods is hindered, and the blood sugar content is reduced, so that the effects of reducing blood sugar and controlling blood sugar are achieved, long-term dependence of diabetics on chemical drugs can be reduced or replaced, damage of the chemical drugs to kidneys and livers can be reduced or avoided, and diabetes can be fundamentally prevented and treatedthrough a dietary therapy method.

The embodiment of the invention discloses substituted tea for reducing blood sugar, which comprises the following components in part by weight: 1 to 3 parts of discolor cinquefoil herb and 3 to 7 parts of platycodon root. The invention also discloses a manufacturing method for the substituted tea for reducing the blood sugar, which comprises the following steps of: (1) weighing the discolor cinquefoil herb and the platycodon root respectively, and picking and cleaning the discolor cinquefoil herb and the platycodon root; (2) drying and sterilizing the treated discolor cinquefoil herb and the treated platycodon root at the temperature of 70 DEG C for later use respectively; and (3) mixing the prepared discolor cinquefoil herb and the prepared platycodon root uniformly in a weight part ratio of the discolor cinquefoil herb to the platycodon root of 1-3: 3-7, and packing the mixture. The substituted tea obtained by the treatment method of the embodiment of the invention has unique taste, is convenient to drink, and has the function of reducing the blood sugar. The manufacturing method for the substituted tea is simple and suitable for large-scale industrialized production. The substituted tea has proper using amount, can be widely suitable for each age group to drink, and is popular for the public.

The invention discloses a method for extracting blood-sugar-lowering banana flower polysaccharide from banana flowers. The method comprises the following steps of (1) crushing; (2) pretreatment: putting banana flower powder into a flask; then, putting the flask into an ultrasound instrument to be treated for 15 min under the conditions of the temperature being 40 to 50 DEG C and the ultrasound powder being 500W to obtain the pretreated banana flower powder; (3) extraction; (4) recovery treatment: putting filter slag into an extraction device; adding protein extracting agents and ferrocene selfassembly body hollow microspheres; performing extraction for 30min at 85 to 100 DEG C; adding hot water being 70 DEG C after liquid removal; performing extraction for 3h under the condition of the pHvalue being 6.5; standing for 12h, collecting water layer extraction liquid to obtain the recovered banana flower polysaccharide solution; (5) separation extraction. The banana flower polysaccharidewith the specified molecular weight can be efficiently extracted; the study basis is provided for the further development of the banana flower polysaccharide.

The present invention discloses grapefruit synthetic and active enzymes and a preparation method thereof, and relates to biological enzymes. The grapefruit synthetic and active enzymes consist of the following raw materials in parts by mass: 25-30 parts of grapefruits, 5-8 parts of lemons, 5-10 parts of minced tea, 1-3 parts of haws, 1-4 parts of traditional Chinese medicinal materials, 10-15 parts of yellow rice wine, 10-15 parts of red granulated sugar and 0.1-0.5 part of acetic acid bacterium. The preparation method of the grapefruit synthetic and active enzymes is as follows: 1) the fruit peels and fruit fleshes of the grapefruits are separated to obtain the grapefruit skins and grapefruit fleshes; 2) the grapefruit skins are cut into blocks, the yellow rice wine is added into the cut grapefruit skin blocks to be soaked, the soaked grapefruit skin blocks are distilled, water is added, and the grapefruit skin blocks are prepared into grapefruit skin wine; and 3) the obtained grapefruit fleshes obtained in the step 1) and the lemons are cut and crushed, the crushed materials are ground into slurry to obtain grapefruit and lemon fruit slurry, then the minced tea, red granulated sugar, haws, traditional Chinese medicinal materials, acetic acid bacteria and the grapefruit skin wine obtained in the step 2) rare successively added, the materials are blended evenly, the mixture is fermented, and the fermented mixture is filtered to obtain the grapefruit synthetic and active enzymes.

The invention discloses a traditional Chinese medicine for effectively treating psychosis, which comprises components with parts by weight: radix glycyrrhizae 2-6 parts, walnut kernels 6-11 parts, sunflower seeds 3-6 parts, achyranthes bidentata 5-10 parts, dried radix rehmanniae 4-9 parts, melodinus suaveolens 6-12 parts, mulberry fruits 5-10 parts, hirudo 3-5 parts, isoeuphpekinensin 7-10 parts, luffa 7-12 parts, peach seeds 5-10 parts, capers 5-10 parts, pteris multifda poir 7-13 parts, christina loosestrife herbs 6-12 parts, amomum 5-10 parts, semen ziziphi spinosae 3-7 parts, nux prinsepiae 5-10 parts, polygala amflra 5-12 parts, semen ziziphi spinosae 7-14 parts and cinnabaris 6-10 parts. The traditional Chinese medicine for effectively treating the psychosis is a special-purpose medicine for treating various psychosis, is based on the theory of traditional Chinese medicine, adopts diagnosis and treatment as a principle, is reasonable in dispensing and convenient to use, and has the effects of eliminating phlegm for resuscitation, restoring consciousness, clearing away heart-fire, calming endogenous wind, arresting convulsion, soothing liver, calming nerves and clearing heat-fire. Compared with the prior art, the traditional Chinese medicine for effectively treating the psychosis has the advantages that the traditional Chinese medicine for effectively treating the psychosis is short in course of treatment, rapid in effect, high in cure rate and not easy to reappear, does not have toxic and side effects, is low in cost, and is easy to be received by patients and the like.

The invention discloses a method for making hongya coptis root tea good for treating diabetes mellitus. The method comprises steps as follows: (1) weighing dry medicinal materials including 10-20 parts of hongya coptis roots, 2-5 parts of great burdock achene, 1-3 parts of corn stigma, 3-5 parts of platycodon roots, 1-2 parts of bitter gourds and 1-2 parts of common macrocarpium fruits, and mixing and smashing the medicinal materials to obtain mixed powder; (2) adding water 10-15 times by weight that of the mixed powder to the mixed powder, decocting the mixture for 30-45 min, performing filtration, re-decocting dregs 2-4 times, adding water 6-10 times by weight that of the mixed powder each time, and combining decocted solutions; (3) concentrating the decocted solution under vacuum until the volume of the decocted solution is 20%-30%; (4) adding a proper amount of sodium benzoate to the concentrated solution, removing oxygen in a vacuum degassing tank and performing filling. The coptis tea is mainly used for treating diabetes mellitus.