Golden camellia blood sugar-lowering granule and preparation method thereof

A technology of golden camellia and granules, which is applied in the field of traditional Chinese medicine, can solve the problems that the medicinal value of traditional Chinese medicine is not reflected, the effect is not ideal, etc., and achieve the effect of ideal hypoglycemic effect, easy implementation, and appropriate components

Inactive Publication Date: 2018-03-02
DALIAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the drugs for clinical treatment of diabetes are mainly insulin, insulin secretory agents, and biguanides. Although the above drugs have good curative effects, they still have some shortcomings, especially in the prevention of diabetic complications.
There are very few preparations on the market that use traditional Chinese medicine to treat diabetes, and the medicinal value of traditional Chinese medicine cannot be reflected. Chinese medicine has great application value in the treatment of diabetes.

Method used

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  • Golden camellia blood sugar-lowering granule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A golden camellia hypoglycemic granule, made from the following raw materials: 15g golden camellia, 6g perilla leaf, 25g tuckahoe, 11g tangerine peel, 5g magnolia bark, 3g bellflower, 12g ginger, 6g Atractylodes macrocephala, 3g pinellia koji, Skin 3g, licorice 8g.

[0032] The preparation method of the above-mentioned golden camellia hypoglycemic granule comprises the following steps:

[0033] (1) According to the ratio, the raw medicinal materials golden camellia, perilla leaf, poria cocos, tangerine peel, magnolia officinalis, bellflower, ginger, Atractylodes macrocephala, Pinellia koji, Dabupi and licorice were washed, dusted and dried to obtain a mixture of raw medicinal materials;

[0034] (2) Add 8 times the amount of 75% ethanol to the mixture obtained in step (1) for reflux extraction, extract 3 times, each time for 1.5h, and combine the extracts;

[0035] (3) drying the extract obtained in step (2) under reduced pressure into a dry extract, and pulverizing in...

Embodiment 2

[0039] A golden camellia hypoglycemic granule, made from the following raw materials: 20g golden camellia, 8g perilla leaf, 30g tuckahoe, 13g tangerine peel, 6g magnolia bark, 3g bellflower, 13g ginger, 6g Atractylodes macrocephala, 3g pinellia koji, Skin 3g, licorice 8g.

[0040] The preparation method of the above-mentioned golden camellia hypoglycemic granule is the same as that in Example 1.

Embodiment 3

[0042] A golden camellia hypoglycemic granule, made from the following raw materials: 30g golden camellia, 10g perilla leaf, 30g tuckahoe, 15g tangerine peel, 6g magnolia bark, 5g bellflower, 13g ginger, 6g Atractylodes macrocephala, 3g pinellia koji, Skin 3g, licorice 10g.

[0043] The preparation method of the above-mentioned golden camellia hypoglycemic granule is the same as that in Example 1.

[0044] Animal experiment 1

[0045] 1. Take 120 experimental mice, half male and half female, weighing 130~150g, and divide them into three groups 1~3, 40 mice in each group. The mice in each group have good physical signs and basically the same physiological characteristics, which are comparable.

[0046] 2. Use the hypoglycemic granules prepared in Examples 1 to 3 of the present invention to be dissolved in water for gavage experiments for four groups of mice, 2 times a day, 10ml (0.1g / ml) each time, for 15 days in a row. The physical signs of all mice were observed and recorde...

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Abstract

The invention relates to the field of traditional Chinese medicine, in particular to a golden camellia hypoglycemic granule and a preparation method thereof. It is made from the following raw materials in parts by weight: 10-30 parts of golden camellia, 1-10 parts of perilla leaves, 15-30 parts of poria cocos, 10-20 parts of tangerine peel, 1-10 parts of Magnolia officinalis, 1-10 parts of bellflower, ginger 10-15 parts, 1-10 parts of Atractylodes macrocephala, 1-10 parts of Pinellia koji, 1-5 parts of Dabupi, 5-10 parts of licorice. The granules of the present invention have proper components and reasonable proportions, have a good effect of lowering blood sugar, have remarkable curative effects on diseases in the initial stage, middle stage and late stage of diabetes, have ideal hypoglycemic effect, and the preparation method is simple and easy to implement, and is suitable for large Large-scale industrial production.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, in particular to a golden camellia hypoglycemic granule and a preparation method thereof. Background technique [0002] In recent years, with the continuous development of society, people's living standards are getting higher and higher, but this has also led to an alarming increase in the number of people with diabetes at home and abroad. According to statistics, one person dies of diabetes every 10 minutes in the world Diabetes-related diseases. Diabetes has become the third major disease after cardiovascular and cerebrovascular diseases and cancer. After scientific research, it has been confirmed that diabetes is a disease that is caused by genetic and environmental factors and endangers human health. According to reports, in 2007, about 38 million people died from the disease, accounting for about 6% of the total global mortality. This number is about the same as the number of A...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/16A61P3/10
CPCA61K36/82A61K9/1652A61K36/076A61K36/284A61K36/346A61K36/484A61K36/535A61K36/575A61K36/752A61K36/8888A61K36/889A61K36/9068A61K2300/00
Inventor 于大永郭秀磊史丽颖
Owner DALIAN UNIV
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