Brain function magnetic resonance imaging method and system

A technology of magnetic resonance imaging and magnetic resonance images, which is applied in medical science, sensors, diagnostic recording/measurement, etc., and can solve problems such as image geometric distortion

Active Publication Date: 2015-02-04
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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Problems solved by technology

[0005] Based on this, it is necessary to provide a new method and system for functional magnetic resonance imaging of the brain to solve the problems of image geometric distortion and Nyquis sampling artifacts in the prior art imaging technology

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  • Brain function magnetic resonance imaging method and system
  • Brain function magnetic resonance imaging method and system
  • Brain function magnetic resonance imaging method and system

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Embodiment Construction

[0075] Based on dynamic brain functional magnetic resonance imaging technology, the present invention provides a method and system for brain functional magnetic resonance imaging, which is based on traditional gradient echo sequences, combined with parallel acquisition, and uses high-order generalized models for reconstruction. This method can avoid High-resolution fMRI imaging is achieved under the premise of image geometric distortion and artifacts. The GS model (Generalized Series: GS) has been applied to dynamic MR imaging, such as diffusion-weighted imaging and cardiac imaging. It only needs to collect a small number of phase encoding lines, which is much smaller than Nyquist sampling, and can reconstruct a high-time resolution image. , but this model cannot capture the detailed features of dynamic images. Therefore, the present invention combines the HGS model of parallel imaging and uses high-frequency items to reconstruct local detail information to improve spatial reso...

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Abstract

The invention provides a brain function magnetic resonance imaging method and system. The method comprises the following steps: obtaining a dynamic data image corresponding to each phased array coil based on multi-channel parallelism and sparse sampling; obtaining a standard image of each phased array coil at an obtaining moment of each dynamic data image according to a first reference image; obtaining a primary function of a high-order generalized-grade model according to the standard image; restraining a grade coefficient of the high-order generalized-grade model by using L2 norms; estimating the grade coefficient based on the dynamic data image and the primary function; reconstructing a middle image corresponding to each time point of each channel based on the high-order generalized-grade model according to an estimated value of the grade coefficient and the standard image; reconstructing the middle image based on a sensitivity matrix of each phased array coil to obtain a reconstructed brain function magnetic resonance image. According to the brain function magnetic resonance imaging method and system, image geometric distortion and Nyquist sampling artifact problems of an imaging technology in the prior art are solved.

Description

technical field [0001] The invention relates to brain functional magnetic resonance imaging technology, in particular to a brain functional magnetic resonance imaging method and system based on a generalized level model. Background technique [0002] Brain functional magnetic resonance imaging (fMRI) measures the hemodynamic response of the brain in the presence of neural activity in the brain. Currently commonly used EPI (Echo-planar imaging) imaging can acquire a slice within a few hundred milliseconds, and the spatial resolution can reach 2-3 mm. However, with the continuous deepening and development of functional imaging research, EPI-based brain functional imaging has Due to the limitations of its own hardware conditions, it is difficult to further improve the spatial and temporal resolution. [0003] The BOLD effect fMRI is based on the principle of changes in the local magnetic field properties caused by the mismatch of neuronal functional activities on local oxygen ...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/055
CPCA61B5/055
Inventor 史彩云谢国喜张晓咏张丽娟刘新
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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