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Carboxymethyl chitosan clysis liquid

A technology of carboxymethyl chitosan and enema liquid, applied in the field of medicine, can solve problems such as small side effects, lack of cleaning effect, etc., and achieve the effects of stable and lasting effect, less pain in use and low degradation rate

Active Publication Date: 2015-02-11
HEBEI AINENG BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Therefore, the prior art lacks a kind of enema solution with good cleaning effect and little side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] formula:

[0026] .

[0027] Preparation:

[0028] Add carboxymethyl chitosan, sodium chloride, and pH value buffer substances in the prescribed amount into water and stir to dissolve; measure the pH value to 7.41, fill and seal; steam sterilize at 100°C for 30 minutes to obtain the product.

Embodiment 2

[0030] formula:

[0031] .

[0032] Preparation:

[0033] Add carboxymethyl chitosan, sodium chloride, and pH value buffer substances in the prescribed amount into water and stir to dissolve; measure the pH value to 7.46, fill and seal; steam sterilize at 100°C for 60 minutes to obtain the product.

Embodiment 3

[0035] formula:

[0036] .

[0037] Preparation:

[0038] Add carboxymethyl chitosan, sodium chloride, and pH value buffer substances in the prescribed amount into water and stir to dissolve; measure the pH value to 7.51, fill and seal; steam sterilize at 100°C for 45 minutes to obtain the product.

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PUM

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Abstract

The invention relates to carboxymethyl chitosan clysis liquid which is prepared from the following components in percentage by mass: 0.3 to 1 percent of carboxymethyl chitosan, 0.8 to 1.5 percent of sodium chloride, 0.01 to 0.1 percent of pH value buffering substance and the balance of water, wherein the pH range of the carboxymethyl chitosan clysis liquid is 7.0 to 7.8. The carboxymethyl chitosan clysis liquid provided by the invention can be used for preoperative intestinal lavage, has a good washing effect, has good compliance for a patient, enables the patient to suffer from small pain and has no adverse effects; the patient can easily tolerate the clysis liquid; the clysis liquid is stable and has little possibility of degrading.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a carboxymethyl chitosan enema used for preoperative intestinal cleaning. Background technique [0002] Intestinal cleaning is generally required before rectal examination or rectal surgery. Usually, the intestinal cleaning method is mainly to perfuse the intestinal tract with a hypertonic solution containing electrolytes, glycerin, or polyethylene glycol. The principle is to use hypertonic The function makes the water in the body seep out from the intestinal tract, softens the stool, and facilitates the excretion of the stool. However, the above methods have many side effects, which can easily cause abdominal pain, discomfort, and even dehydration in the patient, resulting in serious adverse reactions. [0003] In the prior art, there are still many enemas containing drugs, all of which are for therapeutic purposes. The retention of the enemas in the intestinal trac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/42A61P1/10A61K33/14A61K31/722
CPCA61K9/0031A61K31/722A61K33/00A61K33/14A61K33/42A61K2300/00
Inventor 李素哲刘媞董科刘俊英李璟
Owner HEBEI AINENG BIOTECH CO LTD
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