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Three-dimensional array type microfluid sample introduction/cleaning chip

A three-dimensional array and microfluidic technology, applied in instruments, laboratory utensils, analytical materials, etc., can solve the problems of compatibility, unsatisfaction, and unfavorable mass production of biochemical detection chips with general spotting instruments, so as to prevent mutual pollution and high flexibility sexual effect

Inactive Publication Date: 2015-03-25
NANKAI UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] To sum up, the open dot-matrix chip and the microfluidic-type chip have their own advantages, but there are still deficiencies, as follows: (1) The open dot-matrix chip has a simple structure and low cost, and can be used for general-purpose spotting. (2) The microfluidic chip can meet the requirements of fully enclosed experimental operation in the laboratory on a chip, but it is still in the development stage, and the planar chip currently reported Type microfluidic chips are not compatible with general samplers, which is not conducive to the mass production of such biochemical detection chips

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  • Three-dimensional array type microfluid sample introduction/cleaning chip
  • Three-dimensional array type microfluid sample introduction/cleaning chip
  • Three-dimensional array type microfluid sample introduction/cleaning chip

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Embodiment Construction

[0025] Provide the method of use for the present invention:

[0026]The sensor array chip 16 is embedded in the sensor chip embedding frame 15 at the bottom of the sample loading / cleaning chip carrier 8, and the sensor 17 inside the sensor array chip 16 is aligned with the sensitive point window 9 inside the sample loading / cleaning chip carrier 8; the bottom drains The hole 12 communicates with the waste liquid bottle 19 through an external hose 18 and is inserted into the support platform 20 .

[0027] 【references】

[0028] [1] Cai Jinda, Cheng Xi, Liu Cong. Design of automatic biochip sampling detection system, Medical and Health Equipment, February 2009, Volume 30, Issue 2, 58-59.

[0029] [2] Cai Jinda, Cheng Xi, Gan Hanqing, Zhang Jindong, Ma Tianju. Biochip Sample Loading Manipulator Design, Mechanical Design and Manufacturing, July 2009, Issue 7, 22-24.

[0030] [3] Yang Xueqin, Zhong Zhaoyang, Wang Dong, Wang Ge, Yang Zhenzhou, Li Zengpeng, Yang Yuxin, Shen Yibo, W...

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Abstract

The invention relates to a three-dimensional array type microfluid sample introduction / cleaning chip, belonging to the fields of a biosensor and the detection technology of the biosensor. An array type biochemical sensing chip is a novel micromachining, biological / chemical reaction integrated biological and chemical sensitive element, and the three-dimensional array type microfluid sample introduction / cleaning chip can meet the requirement on the closed type full-miniature testing condition of the 'on-chip laboratory', and can be compatible with a full-automatic biological chip sample applicator on the basis of the micromachining processing technology aiming at the requirement of the modern 'on-chip laboratory' for the all-closed miniature testing, and has the advantages of flexibility, low cost and convenience for large-scale production.

Description

[0001] [Technical Field] The present invention belongs to the technical field of biosensors and detection thereof. 【Background technique】 [0002] The array biochemical sensor chip is a new type of biological and chemical sensitive element integrating micromachining and biological / chemical reactions. The traditional array biochemical sensor chip is mainly composed of two parts: the traditional array biochemical sensor Chip carrier 1 and sensitive point 2 (usually a sensor with specific biological and chemical sensitive characteristics). Since this type of chip is mainly used in a liquid environment, the carrier 1 is provided with columnar concave pools 3 arranged in an array to meet the storage requirements for liquid reagents or tested samples; and the sensitive point 2 is located at the bottom of the columnar concave pools 3 ,Such as figure 1 shown. [0003] When the array biochemical sensor chip is actually used, it mainly involves three steps: (1) Functional treatment of...

Claims

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Application Information

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IPC IPC(8): B01L3/00G01N35/00
Inventor 贾芸芳范清杰
Owner NANKAI UNIV