Antihuman-globulin blood matching detection card with different formulas at primary side and secondary side

An anti-human globulin and detection card technology, applied in the field of blood transfusion medicine, can solve the problems of not detecting complement, not detecting complement activation, and missing detection of irregular antibodies, so as to avoid false positives, improve specificity and sensitivity, and improve The effect of sensitivity

Inactive Publication Date: 2015-05-06
许明安
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If the anti-human blood card anti-IgG card is used for blood matching test, irregular antibodies can be detected, but the complement activation caused by irregular antibodies cannot be detected
Clinical studies have shown that irregular antibodies can activate complement components. Complement is not detected in primary-side blood matching, and irregular antibodies will be missed

Method used

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Embodiment Construction

[0006] The present invention will be described in further detail below, so that those skilled in the art can implement it with reference to the description.

[0007] The invention discloses an antihuman globulin blood matching test card with different formulas for the primary and secondary sides, comprising: 6 microcolumn tubes or 8 microcolumn tubes, marking the primary side and the secondary side, numbered 1-6 from left to right Tubes, wherein No. 1, No. 3, and No. 5 tubes are main side tubes, and No. 2, No. 4, and No. 6 tubes are secondary side tubes, and the primary side tubes are used for detecting irregular antibodies and complement components C3D; Tubes for detection of irregular antibodies; the primary side tube contains anti-IgG, anti-C3d, and 0.1%-0.5% NaCl, and the secondary side tube contains anti-IgG, anti-C3d, and 0.2%-0.6% NaCl . The microcolumn tube is formed by pouring gel, glass beads or other granular materials into a plastic tube. The main side tube and t...

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Abstract

The invention discloses an antihuman-globulin blood matching detection card with different formulas at the primary side and the secondary side. The antihuman-globulin blood matching detection card comprises 6 micro-column pipes or 8 micro-column pipes for labeling the primary side and the secondary side, wherein the 6 micro-column pipes are pipes 1-6 in sequence from left to right, i.e., the pipe 1, the pipe 3 and the pipe 5 are the primary-side pipes, and the pipe 2, the pipe 4 and the pipe 6 are secondary-side pipes; the primary-side pipes are used for detecting irregular antibodies and complement component C3d; the secondary-side pipes are used for detecting the irregular antibodies; the primary-side pipes contain anti-IgG, anti-C3d and 0.1%-0.5% of NaCl; and the secondary-side pipes contain anti-IgG and 0.2-0.6% of NaCl. The antihuman-globulin blood matching detection card disclosed by the invention has the advantages that the primary-side pipes and the secondary-side pipes adopt different formulas, so that the specificity and the sensitivity of blood-matching detection are improved and the problems of non-specificity, false positive and false negative generated in blood matching of the primary side and the secondary side in the existing antihuman-globulin detection technology are solved.

Description

technical field [0001] The invention relates to the field of blood transfusion medicine, in particular to a test card for blood matching of antihuman globulin formulas with different primary and secondary sides. Background technique [0002] There are currently several technical options for blood matching: saline blood matching, polybrene blood matching, test tube anti-human blood matching, LISS / Coombs card anti-human blood matching and anti-IgG anti-human blood matching. In cross-matching blood, micro-column centrifugation technology and anti-human card test can be used to detect irregular or incomplete antibodies in samples. The broad-spectrum anti-human card LISS / Coombs card is a product commonly used in the market for anti-human cards, and is mainly used for antibody screening. The anti-IgG anti-human sphere card is mainly used for the research of hemolytic disease of newborns and the detection of irregular antibodies. At present, there is no specific blood matching ca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/80
CPCG01N33/80G01N33/6803
Inventor 许明安
Owner 许明安
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