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Anti-tumor medicine composition

A composition and anti-tumor technology, applied in the direction of anti-tumor drugs, drug combinations, pharmaceutical formulations, etc., can solve problems that have not yet been reported

Inactive Publication Date: 2015-05-20
TIANJIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] The combination of these three drugs involved in the present invention has a very strong anti-tumor effect, and the combination of any two drugs has not been reported yet

Method used

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Examples

Experimental program
Comparison scheme
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Embodiment 1

[0022] An anti-tumor pharmaceutical composition comprises the following components by weight: 91 parts of the extract of Rhizoma chinensis and 9 parts of curcumin.

Embodiment 2

[0024] An anti-tumor pharmaceutical composition comprises the following components by weight: 83 parts of the extract of Rhizoma chinensis, and 17 parts of curcumin.

Embodiment 3

[0026] An anti-tumor pharmaceutical composition comprises the following components by weight: 71 parts of the extract of Rhizoma chinensis and 29 parts of curcumin.

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Abstract

The invention discloses an anti-tumor medicine composition. The medicine composition comprises the following components in parts by weight: 71-91 parts of rhizoma paridis extract and 9-29 parts of curcumin. The composition can be used for remarkably inhibiting growth of LA795 and other lung cancer cell lines and HepG2 and other liver cancer cell lines with IC50 respectively being lower than 20mug / mL; and tests on tumor-bearing mouse models with lung adenocarcinoma, H22 lung cancer, S180 sarcoma and ehrlich ascites tumor indicate that the tumor inhibition rate of the medicine composition is over 50 percent. The medicine composition can be used for increasing the spleen index and thymus index of tumor-bearing mice and improving the living quality of the tumor-bearing mice in comparison with single medicine administration, has high anti-tumor activity, and has a good preventing and treating effect for tumor occurrence.

Description

technical field [0001] The present invention relates to an anti-tumor pharmaceutical composition, in particular to an anti-tumor pharmaceutical composition. Background technique [0002] Cancer is a global public health problem, has become the number one killer in many countries, and will become the disease with the highest morbidity and mortality in the next few decades. The prevention and treatment of cancer has always been a hot topic of research by experts and scholars. Drug therapy is one of the three major therapies for cancer treatment. It began in the 1940s. Compared with surgical treatment and radiation therapy, drug therapy has a much shorter history. However, after decades of development, countries around the world have invented and The total number of anti-tumor drugs approved for use has hundreds of kinds, and the total number of various anti-cancer drug preparations prepared with these raw materials is about 1200-1400 kinds. These drugs are mainly chemotherapy...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P35/00A61K31/12A61K31/4166
Inventor 高文远范亚亚满淑丽刘振李红法高静刘元雪
Owner TIANJIN UNIV
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