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A kind of antitumor pharmaceutical composition

A composition and anti-tumor technology, applied in anti-tumor drugs, drug combinations, pharmaceutical formulations, etc., can solve problems that have not yet been reported

Inactive Publication Date: 2018-05-04
TIANJIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The combination of these three drugs involved in the present invention has a very strong anti-tumor effect, and the combination of any two drugs has not been reported yet

Method used

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  • A kind of antitumor pharmaceutical composition
  • A kind of antitumor pharmaceutical composition
  • A kind of antitumor pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] An anti-tumor pharmaceutical composition comprises the following components by weight: 91 parts of the extract of Rhizoma chinensis and 9 parts of curcumin.

Embodiment 2

[0024] An anti-tumor pharmaceutical composition comprises the following components by weight: 83 parts of the extract of Rhizoma chinensis, and 17 parts of curcumin.

Embodiment 3

[0026] An anti-tumor pharmaceutical composition comprises the following components by weight: 71 parts of the extract of Rhizoma chinensis and 29 parts of curcumin.

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Abstract

The invention discloses an anti-tumor pharmaceutical composition, which comprises the following components by weight: 71-91 parts of the extract of the plant, and 9-29 parts of curcumin. The composition of the present invention can significantly inhibit the growth of lung cancer cell lines such as LA795 and liver cancer cell lines such as HepG2, and the IC50 can reach below 20 μg / mL respectively; Mouse model experiments show that the tumor inhibition rate is above 50%. Compared with the single drug administration group, it can increase the spleen index and thymus index of tumor-bearing mice, and improve the quality of life of tumor-bearing mice. The pharmaceutical composition has anti-tumor The activity is very high, and it has a good preventive and therapeutic effect on the occurrence of tumors.

Description

technical field [0001] The present invention relates to an anti-tumor pharmaceutical composition, in particular to an anti-tumor pharmaceutical composition. Background technique [0002] Cancer is a global public health problem, has become the number one killer in many countries, and will become the disease with the highest morbidity and mortality in the next few decades. The prevention and treatment of cancer has always been a hot topic of research by experts and scholars. Drug therapy is one of the three major therapies for cancer treatment. It began in the 1940s. Compared with surgical treatment and radiation therapy, drug therapy has a much shorter history. However, after decades of development, countries around the world have invented and The total number of anti-tumor drugs approved for use has hundreds of kinds, and the total number of various anti-cancer drug preparations prepared with these raw materials is about 1200-1400 kinds. These drugs are mainly chemotherapy...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K36/896A61P35/00A61K31/12A61K31/4166
Inventor 高文远范亚亚满淑丽刘振李红法高静刘元雪
Owner TIANJIN UNIV
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