Traditional Chinese medicine composition for treating chronic lymphocytic thyroiditis and preparation method thereof
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A technology for lymphocytes and thyroiditis, applied in the field of preparation of traditional Chinese medicine compositions, can solve the problems of abnormal quantity and quality of T lymphocytes, lack of system integrity, incomplete mechanism and the like
Active Publication Date: 2015-06-24
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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2. Immunological factors The mechanism of thyroid damage caused by immunological factors is not completely clear
At present, the following mechanisms tend to be more likely: (1) Congenital immune surveillance defects: lead to abnormal quantity and quality of organ-specific suppressive T lymphocytes, T lymphocytes can directly attack thyroid follicular cells
Although all have achieved certain curative effects, they have more one-sided limitations and lack of system integrity
Method used
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Embodiment 1
[0020] Weigh 1,000 grams of raw Astragalus membranaceus, 1,000 grams of Radix Ginseng, and 1,000 grams of Ganoderma lucidum, add four times the amount of water, decoct for 1.5 hours, filter, concentrate to a clear paste with a relative density of about 1.35 (80°C), add appropriate amount of dextrin, Granulate (14-16 mesh), vacuum dry (80°C), and pack.
Embodiment 2
[0022] Weigh 1,000 grams of raw Astragalus membranaceus, 2,000 grams of Radix Adenophora, and 1,000 grams of Ganoderma lucidum, add 6 times the amount of 75% ethanol, reflux extraction twice, decoct for 1.5 hours, filter, combine the filtrates, recover ethanol until it has no alcohol smell, and concentrate to For a clear paste with a relative density of about 1.35 (80°C), add an appropriate amount of dextrin, granulate (14-16 mesh), vacuum dry (80°C), and pack.
Embodiment 3
[0024] Weigh 1,000 grams of raw Astragalus membranaceus, 3,000 grams of Radix Adenophora, and 1,000 grams of Ganoderma lucidum, add 8 times the amount of 90% ethanol, reflux extraction three times, decoct for 1.5 hours, filter, combine the filtrates, recover the ethanol until it has no alcohol smell, and concentrate to a relatively For a clear paste with a density of about 1.35 (80°C), add appropriate amount of dextrin, granulate (14-16 mesh), vacuum dry (80°C), and pack.
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Abstract
The invention discloses a traditional Chinese medicine composition for treating chronic lymphocytic thyroiditis. The traditional Chinese medicine composition is a medicament prepared from the raw material medicines in parts by weight: 10-30 parts of astragalus membranaceus, 10-30 parts of radix glehniae, and 10-30 parts of lucid ganoderma. The traditional Chinese medicine composition is suitable for the patients with qi and yin deficiency pattern and syndrome of loss of control due to deficient root of the chronic lymphocytic thyroiditis. The clinical research for treating the chronic lymphocytic thyroiditis shows that the effective rate for reducing the indexes of the antithyroglobulin antibody (TG-Ab) and the antithyroid peroxidase antibody (TPo-Ab) and changing the symptom is 80%. The invention also discloses a preparation method of the traditional Chinese medicine composition granule.
Description
technical field [0001] The invention relates to a traditional Chinese medicine composition for treating chronic lymphocytic thyroiditis (chronic lymphocytic thyroiditis, CLT is also called autoimmune thyroiditis); the invention also relates to a preparation method of the traditional Chinese medicine composition. Background technique [0002] In recent years, due to environmental factors such as genetic factors, diet factors, tense pace of life, and increased work pressure, the incidence of autoimmune thyroid diseases has increased year by year, among which Hashimoto's thyroid disease is the most common. Hashimoto of Kyushu University in Japan first (1912) reported 4 cases in the German Medical Journal and named it Hashimoto (Hashimoto) thyroiditis (Hashimotos thyroiditis, HT), which is the most common thyroid inflammation in clinical practice. In recent years, the incidence has increased rapidly, and it has been reported that it is similar to the incidence of hyperthyroidism...
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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61K9/16A61P5/14A61P37/02
Inventor 李红徐蓉娟
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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