A kind of preparation method of chitosan-based wound dressing of aromatic antibacterial
A wound dressing and chitosan technology, applied in the field of medical materials, can solve the problems of short antibacterial action time, reduce the concentration of essential oils, affect the efficacy of sterilization, etc., achieve significant antibacterial effect, optimize the environment, and pleasant mood effects.
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Embodiment 1
[0043] A kind of preparation method of chitosan-based wound dressing of aromatic antibacterial:
[0044] (1) Tea tree essential oil, menthol and Artemisia argyi essential oil were stirred at 60 rpm at 4°C in a mass ratio of 1:1:1. Add 8g of sodium chloride, 0.2 g / L of potassium chloride, 1.44g of disodium hydrogen phosphate, and 0.24g of dipotassium hydrogen phosphate into 800ml of water, stir to fully dissolve, adjust the pH value to 6.5 with hydrochloric acid, and add water to 1000ml , Add 60g Tween 80 to obtain a phosphate buffer solution. Add the essential oil mixture to the phosphate buffer solution at a concentration of 1g / 100mL to obtain the natural aromatic antibacterial agent;
[0045] (2) Dissolve 100mg of soybean lecithin and 25mg of cholesterol in chloroform and pour it into a round-bottomed flask, and rotate it at room temperature until a uniform film is formed on the wall of the bottle; dissolve 10ml of natural aromatic antibacterial agent in an ultrasonic water...
Embodiment 2
[0049] A kind of preparation method of chitosan-based wound dressing of aromatic antibacterial:
[0050] (1) Tea tree essential oil, menthol and Artemisia argyi essential oil were stirred at 60 rpm at 4°C in a mass ratio of 1:1:1. Add 8g of sodium chloride, 0.2 g / L of potassium chloride, 1.44g of disodium hydrogen phosphate, and 0.24g of dipotassium hydrogen phosphate into 800ml of water, stir to fully dissolve, adjust the pH value to 6.5 with hydrochloric acid, and add water to 1000ml , Add 60g Tween 80 to obtain a phosphate buffer solution. Add the essential oil mixture to the phosphate buffer solution at a concentration of 0.2g / 100mL to obtain the natural aromatic antibacterial agent;
[0051] (2) Dissolve 100mg of soybean lecithin and 25mg of cholesterol in chloroform and pour it into a round-bottomed flask, and rotate it at room temperature until a uniform film is formed on the wall of the bottle; dissolve 10ml of natural aromatic antibacterial agent in an ultrasonic wat...
Embodiment 3
[0055] A kind of preparation method of chitosan-based wound dressing of aromatic antibacterial:
[0056] (1) Tea tree essential oil, menthol and Artemisia argyi essential oil were stirred at 60 rpm at 4°C in a mass ratio of 1:1:1. Add 8g of sodium chloride, 0.2 g / L of potassium chloride, 1.44g of disodium hydrogen phosphate, and 0.24g of dipotassium hydrogen phosphate into 800ml of water, stir to fully dissolve, adjust the pH value to 6.5 with hydrochloric acid, and add water to 1000ml , Add 60g Tween 80 to obtain a phosphate buffer solution. Add the essential oil mixture to the phosphate buffer solution at a concentration of 2g / 100mL to obtain a natural aromatic antibacterial agent;
[0057] (2) Dissolve 100mg of soybean lecithin and 25mg of cholesterol in chloroform and pour it into a round-bottomed flask, and rotate it at room temperature until a uniform film is formed on the wall of the bottle; dissolve 10ml of natural aromatic antibacterial agent in an ultrasonic water b...
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