Traditional Chinese medicine composition for treating fatty liver combined hyperlipidemia and preparation method thereof

A composition and high blood fat technology, applied in the field of medicine, to achieve the effect of easy to obtain raw materials, good application prospects, and comprehensive drug effects

Inactive Publication Date: 2015-09-09
QINGDAO CHENDA BIOLOGICAL SCI & TECH
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AI-Extracted Technical Summary

Problems solved by technology

It is challenging for people to seek single-drug active ingredients or comp...
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Abstract

The invention relates to a traditional Chinese medicine composition for treating fatty liver combined hyperlipidemia and a preparation method thereof. Aiming at the defect of uncertain treatment effect of medicines for treating the fatty liver combined hyperlipidemia in the prior art, the invention provides the traditional Chinese medicine composition for treating or preventing a fatty liver. The traditional Chinese medicine composition comprises the following components: 10 parts of rhizoma smilacis glabrae, 6 parts of rehmannia glutinosa libosch, 10 parts of radix sophorae flavescentis, 10 parts of radix polygonum multiflorum preparata, 20 parts of bighead atractylodes rhizome, 20 parts of red peony root extract, 10 parts of rhizoma corydalis, 15 parts of cassia twig, 30 parts of caulis spatholobi, 5 parts of centella, 6 parts of capillary artemisia and 10 parts of turmeric. The traditional Chinese medicine composition can obviously lower the level of transaminase of a fatty liver patient in a clinical application, has an active treatment effect of lowering blood fat and is very suitable for being clinically used by a patient with the fatty liver combined hyperlipidemia.

Application Domain

Metabolism disorderDigestive system +2

Technology Topic

Sophora flavescensPharmaceutical drug +13

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  • Traditional Chinese medicine composition for treating fatty liver combined hyperlipidemia and preparation method thereof

Examples

  • Experimental program(4)

Example Embodiment

[0014] Example 1 The traditional Chinese medicine composition mixture of the present invention
[0015] Prescription: 10 parts of Smilax glabra, 6 parts of Habitat, 10 parts of Sophora flavescens, 10 parts of Polygonum multiflorum, 20 parts of Atractylodes macrocephala, 20 parts of Radix Paeoniae Rubra, 10 parts of Yuanhu, 15 parts of Cassia twig, 30 parts of Caulis spatholobi, Centella asiatica 5 parts of grass, 6 parts of grass, 10 parts of turmeric.
[0016] Preparation method: Take each medicinal material of the above weight components, add 5 times the total weight of the medicinal material in water, soak for 30 minutes, decoct 2 times, 2 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.1 The relative density of the extract is measured at 60 degrees Celsius. Add ethanol to 75% alcohol (v/v), let it stand for 24 hours, take the supernatant, recover the ethanol, concentrate, and dry to obtain the Chinese medicine Extract; crush it into dry powder and add a prescription amount of red peony extract to obtain the traditional Chinese medicine composition of the present invention. Add water to 1000ml, stir evenly, dispense, and sterilize by circulating steam for 35 minutes to obtain the mixture.

Example Embodiment

[0017] Example 2 Chinese medicine composition tablet of the present invention
[0018] Prescription: 10 parts of Smilax glabra, 6 parts of raw place, 10 parts of Sophora flavescens, 10 parts of Polygonum multiflorum, 20 parts of Atractylodes macrocephala, 20 parts of Radix Paeoniae Rubra, 10 parts of Yuanhu, 15 parts of Cassia twig, 30 parts of Caulis spatholobi, Centella asiatica 5 parts of grass, 6 parts of grass, 10 parts of turmeric.
[0019] Preparation method: Take each medicinal material of the above weight components, add 10 times the total weight of the medicinal material in water, soak for 60 minutes, decoct once for 1 hour, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The relative density is the test result at 60 degrees Celsius. Add ethanol to 80% alcohol content (v/v), let stand for 24 hours, take the supernatant, recover the ethanol to concentrate, and dry it. Chinese medicinal extract: After pulverizing it into dry powder, adding a prescription amount of red peony extract to obtain the Chinese medicinal composition of the present invention, vacuum drying, granulating, and tableting.

Example Embodiment

[0020] Example 3 Chinese medicine composition capsules of the present invention
[0021] Prescription: 10 parts of Smilax glabra, 6 parts of raw place, 10 parts of Sophora flavescens, 10 parts of Polygonum multiflorum, 20 parts of Atractylodes macrocephala, 20 parts of Radix Paeoniae Rubra, 10 parts of Yuanhu, 15 parts of Cassia twig, 30 parts of Caulis spatholobi, Centella asiatica 5 parts of grass, 6 parts of grass, 10 parts of turmeric.
[0022] Preparation method: Take each medicinal material of the above weight components, add 8 times the total weight of the medicinal material in water, soak for 45 minutes, decoct 4 times, 1.5 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.2 The relative density is the test result at 60 degrees Celsius. Add ethanol to 90% alcohol content (v/v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, and dry it. Chinese medicinal extract: After pulverizing it into dry powder, adding a prescription amount of red peony extract to obtain the Chinese medicinal composition of the present invention, vacuum drying, granulating, and encapsulating it.
[0023] The second part, the pharmacodynamic investigation of the traditional Chinese medicine composition of the present invention
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Description & Claims & Application Information

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