Application of traditional Chinese medicine composition to preparation of drug for resisting Middle East respiratory syndrome corona-virus (MERS-CoV)

A technology of coronavirus and composition, which is applied in the direction of antiviral agents, drug combinations, active ingredients of hydroxyl compounds, etc., and can solve problems such as the application of undisclosed traditional Chinese medicine composition against Middle East novel coronavirus

Inactive Publication Date: 2015-11-25
BEIJING YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The above-mentioned patent does not disclose the application of the traditional Chinese

Method used

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  • Application of traditional Chinese medicine composition to preparation of drug for resisting Middle East respiratory syndrome corona-virus (MERS-CoV)
  • Application of traditional Chinese medicine composition to preparation of drug for resisting Middle East respiratory syndrome corona-virus (MERS-CoV)
  • Application of traditional Chinese medicine composition to preparation of drug for resisting Middle East respiratory syndrome corona-virus (MERS-CoV)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] prescription:

[0068] Forsythia 255g Honeysuckle 255g Banlangen 255g Rhubarb 51g

[0069] Patchouli 85g Mianma Guanzhong 255g Rhodiola 85g Menthol 7.5g

[0070] 85 grams of roasted ephedra 85 grams of fried bitter almonds 255 grams of Houttuynia cordata

[0071] 85 grams of licorice and 255 grams of gypsum.

[0072] Preparation:

[0073] (1) Take Chinese medicinal materials according to the above prescription, and select them;

[0074] (2) Patchouli is broken, add 6 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0075] (3) forsythia, ephedra, houttuynia cordata, and rhubarb, extracted twice with 8 times the amount of 70% ethanol, the first time for 2 hours, the second time for 1.5 hours, the extracts were combined and filtered, the ethanol was recovered, and the filtrate was used for later u...

Embodiment 2

[0081] prescription:

[0082] Forsythia 200g Honeysuckle 300g Banlangen 200g Rhubarb 60g Patchouli 60g Mianma Guanzhong 300g Rhodiola 60g Menthol 9g

[0083] 60 grams of roasted ephedra 100 grams of fried bitter almonds 200 grams of Houttuynia cordata

[0084] 100 grams of licorice and 200 grams of gypsum.

[0085] Preparation:

[0086] (1) Take Chinese medicinal materials according to the above prescription, and select them;

[0087] (2) Patchouli is broken, add 5 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0088] (3) Forsythia japonicus, roasted ephedra, Houttuynia cordata, and rhubarb were extracted twice with 6 times the amount of 50% ethanol, the first time was 1 hour, and the second time was 2.5 hours, the extracts were combined and filtered, the ethanol was recovered, and the filtrate was u...

Embodiment 3

[0094] prescription:

[0095] Forsythia 300g Honeysuckle 200g Banlangen 300g Rhubarb 40g

[0096] Patchouli 100g Mianma Guanzhong 200g Rhodiola 100g Menthol 5g Sun-baked Ephedra 100g Fried Bitter Almond 60g Houttuynia cordata 300g

[0097] 60 grams of licorice and 300 grams of gypsum.

[0098] Preparation:

[0099] (1) Take Chinese medicinal materials according to the above prescription, and select them;

[0100] (2) Patchouli is broken, add 8 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0101] (3) forsythia, ephedra, houttuynia cordata, and rhubarb, extracted twice with 10 times the amount of 90% ethanol, the first time for 3 hours, the second time for 2.5 hours, the extracts were combined and filtered, the ethanol was recovered, and the filtrate was used for later use;

[0102] (4) Honeysuckle, ...

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Abstract

The invention discloses application of a traditional Chinese medicine composition to preparation of a drug for resisting the Middle East respiratory syndrome corona-virus (MERS-CoV). The traditional Chinese medicine composition is composed of fructus forsythia, honeysuckle, indigowoad root, rheum officinale, herba pogostemonis, rhizoma dryopteris crassirhizomae, rhodiola rosea and the like. The whole adjustment advantage of the compound traditional Chinese medicine is brought into play, the effects of removing pathogenic factors, relieving symptoms and regulating immunity are organically combined, and clinical experiment results show that the medicine provided by the invention has the effects of resisting the MERS-CoV.

Description

Technical field [0001] The invention involves the application of a Chinese medicine composition in preparing for the anti -new coronary virus drug in the Middle East, which belongs to the field of Chinese herbal medicine. Background technique [0002] The new Coronatte virus in the Middle East, referred to as MERS-COV, was first discovered in the Middle East. It was a unified new type of coronary virus name and promoted the report of the case of new coronary virus infection.The syndrome coronary virus "and announced on May 15, 2013 in the Virus Magazine, the name of the disease is" Middle East Breathing Syndrome ", and English is referred to as" MERS ".Due to the dense population and crowded population, and hot weather, a new type of coronary virus infection was found in Saudi Arabia. Most of the confirmed cases were concentrated in the Middle East countries, but some European countries reported the disease one after another.Traveling in the UAE, in France and the United Kingdom,...

Claims

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Application Information

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IPC IPC(8): A61K36/78A61P31/14A61P37/04A61K33/06A61K31/045
Inventor 贾振华魏聪常丽萍袁国强赵军红
Owner BEIJING YILING PHARMA
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