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Extracting method and application of plant composition containing radix pseudostellariae

An extraction method and technology of heterophylla, which can be applied to drug combinations, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of large dosage for patients, rough process, and impact on clinical application, and achieve the effect of reducing dosage

Inactive Publication Date: 2015-12-16
南京多宝生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing Radix Pseudostellariae. However, the method of decocting in water is rough and backward, with many impurities, which leads to excessive dosage for patients and is inconvenient to take. Seriously affected the clinical application of this product

Method used

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  • Extracting method and application of plant composition containing radix pseudostellariae
  • Extracting method and application of plant composition containing radix pseudostellariae

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Take 100g of Radix Pseudostellariae, 80g of wild hops, 50g of Adenophora toothache, 170g of Tiejuopan powder, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, and the extraction is performed twice. For 4-8 minutes, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain microwave extraction Add conventional excipients and prepare into tablets, 0.4g per tablet.

Embodiment 2

[0016] Take 100g of Radix Pseudostellariae, 80g of wild hops, 50g of Adenophora toothache, 170g of Tiejuopan powder, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, and the extraction is performed twice. For 4-8 minutes, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain microwave extraction and add conventional excipients to prepare capsules.

Embodiment 3

[0018] Take 100g of Radix Pseudostellariae, 80g of wild hops, 50g of Adenophora toothache, 170g of Tiejuopan powder, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, and the extraction is performed twice. For 4-8 minutes, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain microwave extraction The product is prepared into granules by adding conventional excipients.

[0019] Wild hops, Latin name Humuluslupulus L.Var. Cordifolius (Miq.) Maxim., is the flower of Moraceae Huahubu. Bitter in the mouth, flat in nature. Go into the heart, lung, stomach warp. Stomach invigorating, sedative, anti-tuberculosis. Treat indigestion, not thinking about eating, hysteria, insomnia, tuberculosis.

[0020] Pterygiella adenophora is ...

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Abstract

The invention provides an extracting method of a plant composition containing radix pseudostellariae. The plant composition is prepared from 100 g of radix pseudostellariae, 80 g of humulus lupulus, 50 g of ctenium aromaticum and 170 g of schisandra propinqua and is prepared through the microwave extraction method. In this way, the content is greatly increased, and the usage amount is reduced. The invention further provides an application of the plant composition containing radix pseudostellariae in preparation of medicine for restraining brown rat insulinoma epithelium RIN-m proliferation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an extraction method and application of a plant composition containing Radix Pseudostellariae. Background technique [0002] The plant composition containing Pseudostellaria Pseudostellariae is made from 100g Pseudostellariae Pseudostellariae, 80g wild hops, 50g Adenophora japonica, and 170g Tiejuopan as raw materials. The current extraction method is to decoct twice with water, each time for 2-3 hours, Combine the decoctions, filter, condense into a thick paste, granulate, dry, press into 1000 tablets, and coat with sugar, that is, it can improve immunity. [0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing Radix Pseudostellariae, but the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for pati...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/80A61P35/00
Inventor 李洋
Owner 南京多宝生物科技有限公司
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