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Medicine composition for preventing and treating nephrosis

A technology for compositions and medicines, applied in the directions of medicine combinations, active ingredients of heterocyclic compounds, pharmaceutical formulations, etc., can solve the problems of limited scope and poor results.

Inactive Publication Date: 2015-12-23
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the scope of western medicine is limited in the treatment of diabetic nephropathy. It basically treats symptoms by lowering blood sugar, lowering lipids, or using ACEI and ARB drugs, but the results are not good.

Method used

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  • Medicine composition for preventing and treating nephrosis

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: the pharmaceutical composition of preventing and treating nephropathy and preparation method thereof

[0038] The composition and parts by weight of the bulk drug of the pharmaceutical composition for preventing and treating nephropathy are:

[0039] 140 parts by weight of golden waist grass, 100 parts by weight of delphinium 100 parts by weight, 70 parts by weight of lapis lazuli, 9 parts by weight of aucubin, 5 parts by weight of carbubuginin, 2 parts by weight of protopetine;

[0040] Preparation:

[0041] (1) Take delphinium and lapis lazuli according to the ratio of raw materials, mix well, first use 80% ethanol as a solvent, and extract at 55°C by warm soaking, the number of extractions is 4 times, and the extraction time for each time is 3 hour, each solvent consumption is 20 times of the total weight of Delphinium pilosula and lapis lazuli medicinal materials, filter to obtain medicinal residue A and extract, the extract reclaims ethanol, concentr...

Embodiment 2

[0044] Embodiment 2: the pharmaceutical composition of preventing and treating nephropathy and preparation method thereof

[0045] The composition and parts by weight of the bulk drug of the pharmaceutical composition for preventing and treating nephropathy are:

[0046] 130 parts by weight of golden waist grass 110 parts by weight of delphinium 110 parts by weight of lapis lazuli 60 parts by weight of aucubin 10 parts by weight of aucubinin 4 parts by weight of protopetine 3 parts by weight;

[0047] Preparation:

[0048] (1) Take delphinium and lapis lazuli according to the ratio of raw materials, mix well, first use 80% ethanol as a solvent, and extract at 55°C by warm soaking, the number of extractions is 4 times, and the extraction time for each time is 3 hour, each solvent consumption is 20 times of the total weight of Delphinium pilosula and lapis lazuli medicinal materials, filter to obtain medicinal residue A and extract, the extract reclaims ethanol, concentrates, a...

Embodiment 3

[0051] Embodiment 3: the pharmaceutical composition of preventing and treating nephropathy and preparation method thereof

[0052] The composition and parts by weight of the bulk drug of the pharmaceutical composition for preventing and treating nephropathy are:

[0053] 150 parts by weight of golden waist grass 90 parts by weight of delphinium 90 parts by weight of lapis lazuli 80 parts by weight of aucubin 8 parts by weight of carapeutenin 6 parts by weight of propatine 1 weight part;

[0054] Preparation:

[0055] (1) Take delphinium and lapis lazuli according to the ratio of raw materials, mix well, first use 80% ethanol as a solvent, and extract at 55°C by warm soaking, the number of extractions is 4 times, and the extraction time for each time is 3 hour, each solvent consumption is 20 times of the total weight of Delphinium pilosula and lapis lazuli medicinal materials, filter to obtain medicinal residue A and extract, the extract reclaims ethanol, concentrates, and dri...

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Abstract

The invention discloses a medicine composition for preventing and treating nephrosis and a preparation method thereof. The medicine composition is prepared by mixing chrysosplenium nudicaule bunge, herba delphinii, lapis lazuli, aucubin, sarcostemma acidum aglycone and protostemonine, which are used as active ingredients. The medicine composition can be made into various preparations according to a conventional preparation process, and the curative effect for preventing and treating the nephrosis is remarkable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for preventing and treating nephropathy and a preparation method thereof. Background technique [0002] Diabetic nephropathy is also called diabetic glomerulosclerosis. Diabetic nephropathy is the most common microvascular complication of diabetes, and it is also the root cause of chronic renal failure. The course of diabetic nephropathy is generally 10 to 20 years, and the incidence of diabetic nephropathy reaches about 50%. Patients with diabetic nephropathy have proteinuria for about 7 years, and half of them will become end-stage renal disease. According to authoritative data, the incidence of diabetic nephropathy in diabetic patients within 10 to 20 years reaches 47.66%, and the lesions show progressive development, and end-stage renal failure will occur within 5 to 10 years. Clinical pathological studies of wes...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61P13/12A61K31/55A61K31/7048A61K33/06A61K31/57
Inventor 张秀华
Owner JINAN XINGYI MEDICAL TECH
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