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Method for extracting plant composition containing echinacea and application of plant composition

An extraction method, the technology of Echinacea purpurea, applied in the direction of drug combination, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of large dosage, backwardness, and many impurities for patients, and achieve the effect of reducing dosage

Inactive Publication Date: 2015-12-30
NANJING ZHENGLIANG MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, there is no report on the extraction and preparation of plant compositions containing Echinacea purpurea using microwave technology, but the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for patients, which is inconvenient to take, and seriously Affected the clinical application of this product

Method used

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  • Method for extracting plant composition containing echinacea and application of plant composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Get 100 parts of Echinacea purpurea, 20 parts of Three Point Golden Grass, 50 parts of Landing Root, 40 parts of Hanging White Leaf, and 50 parts of Water Gardenia Leaf, grind them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, extract twice, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, and recover under reduced pressure Ethanol, concentrated and dried to obtain a microwave extract, and prepared into tablets with conventional excipients, each tablet 0.4g.

Embodiment 2

[0016] Get 100 parts of Echinacea purpurea, 20 parts of Three Point Golden Grass, 50 parts of Landing Root, 40 parts of Hanging White Leaf, and 50 parts of Water Gardenia Leaf, grind them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, extract twice, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, and recover under reduced pressure Ethanol, concentrated and dried to obtain a microwave extract, which is prepared into capsules with conventional auxiliary materials.

Embodiment 3

[0018] Get 100 parts of Echinacea purpurea, 20 parts of Three Point Golden Grass, 50 parts of Landing Root, 40 parts of Hanging White Leaf, and 50 parts of Water Gardenia Leaf, grind them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, extract twice, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, and recover under reduced pressure Ethanol, concentrated and dried to obtain a microwave extract, which is prepared into granules by adding conventional auxiliary materials.

[0019] San Dian Jin Cao, scientific name: Desmodium triflorum (L.) DC.), Fabaceae, Papilionaceae, mountain leech family, promoting qi and relieving pain, warming meridian and dispelling cold, detoxification. For heat stroke abdominal pain, hernia pain, irregular menstruation, dysmenorrhea, postpartum joint...

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Abstract

The invention provides a method for extracting a plant composition containing echinacea. The method is prepared from 100 parts of echinacea, 20 parts of desmodium triflorum, 50 parts of kalanchoe pinnatum, 40 parts of tubeflower viburnum herb and 50 parts of large-flowered gardenia leaves. A microwave extraction method is used for preparation, so that the content is greatly increased, and the using amount is reduced. The invention further provides an application of the plant composition containing the echinacea to preparation of P19 cell proliferation drugs for inhibiting mouse teratoma.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an extraction method and application of a plant composition containing echinacea purpurea. Background technique [0002] The plant composition containing Echinacea purpurea is made of 100 parts of Echinacea purpurea, 20 parts of three-point golden grass, 50 parts of ground root, 40 parts of hanging white leaves, and 50 parts of water gardenia leaves. The current extraction method is to add water and decoct twice , every 2-3 hours, combined decoction, filtered, concentrated into a thick paste, granulated, dried, sugar-coated, that is. [0003] In the prior art, there is no report on the extraction and preparation of plant compositions containing Echinacea purpurea using microwave technology, but the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for patients, which is inconvenient to take,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61P35/00
Inventor 赵明亮
Owner NANJING ZHENGLIANG MEDICAL TECH
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