Superovulation polyvinylpyrrolidone FSH composite slow-release injection for sika deer

A technology of polyvinylpyrrolidone and slow-release injections, which can be used in drug combinations, medical preparations containing no active ingredients, medical preparations containing active ingredients, etc., and can solve problems such as poor superovulation effects

Inactive Publication Date: 2016-07-06
INST OF SPECIAL ANIMAL & PLANT SCI OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned materials are commonly used drugs to promote ovulation and pregnancy in female animals, but in actual use, the effect of this slow-release age

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Add 1300 international units of FSH, 0.8 grams of acid xylase and 0.9 grams of cellulase to 1.2 grams of polyvinylpyrrolidone, then add 21 milliliters of double distilled water, mix well, add 50,000 units of gentamicin, and mix Uniformly made superovulation slow-release agent. Its release effect can ensure that the medicine used in the method is released uniformly 24 hours a day.

Embodiment 2

[0016] Add 1400 international units of FSH, 1.1 g of acid xylase and 0.8 g of cellulase to 1.4 g of polyvinylpyrrolidone (PVP), then add 22 ml of double distilled water, mix well, and then add 60,000 units of gentamicin Elements, mixed evenly to make a superovulation slow-release agent. Its release effect can ensure that the medicine used in the method is released uniformly 24 hours a day.

Embodiment 3

[0018] Add 1500 international units of FSH, 1.3 grams of acid xylase and 0.6 grams of cellulase to 1.6 grams of polyvinylpyrrolidone, then add 24 milliliters of double distilled water, mix well, add 80,000 units of gentamicin, and mix Evenly made superovulation agent. Its release effect can ensure that the medicine used in the method is released uniformly 24 hours a day.

[0019] The following test examples show the effect of the present invention on superovulation of sika deer:

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PUM

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Abstract

The invention provides a superovulation polyvinylpyrrolidone FSH composite slow-release injection for sika deer. Four substances, such as FSH, acidic xylosidase, cellulase and gentamicin, are uniformly dispersed in polyvinylpyrrolidone so as to form a slow release agent; and according to a synergistic effect of medicines such as FSH, acidic xylosidase, cellulose, gentamicin and the like, target substances and indirectly produced nutrient substances can continuously and uniformly act on ovary cells so as to promote follicle growth and maturity; and therefore, a good effect on superovulation is achieved, and the mature ovum is high in quality. According to the dosage form, stress reaction is reduced by intravenous injection, and intense struggling caused by pain is alleviated.

Description

technical field [0001] The invention provides a superovulation polyvinylpyrrolidone FSH composite slow-release injection for sika deer, which belongs to the technical field of livestock medicine preparation. Background technique [0002] FSH is the English abbreviation of follicle-stimulating hormone, which is a glycoprotein. The physiological function of FSH is to promote the growth of ovarian follicles; promote the proliferation of follicular granulosa cells and the synthesis and secretion of estrogen, and stimulate the production of LH receptors on follicular cells. FSH is used for superovulation in dams. [0003] FSH is a hormone that promotes follicle development, and the addition of acid xylosidase and cellulase promotes the release of various nutrients required by follicles. The above-mentioned drugs can only be made into slow-release formulations together with polyvinylpyrrolidone. It can slow down the release speed and uniformity of PMSH, acid xylase and cellulase...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K38/24A61K38/47A61K31/7036A61K47/32A61P15/08
CPCA61K38/24A61K9/0002A61K9/0019A61K9/08A61K31/7036A61K38/47A61K47/32C12Y302/01C12Y302/01004
Inventor 赵蒙常忠娟曹新燕赵伟刚许保增徐超杨镒峰薛海龙陈秀敏
Owner INST OF SPECIAL ANIMAL & PLANT SCI OF CAAS
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