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Multichannel three-dimensional nuclear magnetic resonance imaging method based on 1H-19F-23Na atomic nucleus

A nuclear magnetic resonance imaging and atomic nucleus technology, applied in magnetic resonance measurement, magnetic variable measurement, medical science, etc., can solve the problem of losing the best treatment time for tumors, so as to break the monopoly of medical technology, improve the cure rate of tumors, and improve survival quality effect

Inactive Publication Date: 2016-07-20
HARBIN MEDICAL UNIVERSITY
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Problems solved by technology

[0003] However, traditional nuclear magnetic resonance technology can only provide anatomical image information, and the tumor can only be diagnosed when it develops to the middle and late stage, causing many cancer patients to lose the best time for tumor treatment

Method used

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Embodiment Construction

[0016] The following describes the technical solutions in the embodiments of the present invention clearly and completely. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.

[0017] The present invention adopts magnetic resonance pulse sequence 1H / 23NaPANSY-COSY, 23Na-23NaCOSY, 1 H / 19 FPANSY-COSY or 1H / 19F / 23NaPANSY-COSY scans the part to be imaged. The reason is that 19F nuclear has the following advantages in NMR research:

[0018] (1) The spin quantum number of the 19F nucleus is 1 / 2, and its abundance in nature is 100%. The 19F nucleus has a high sensitivity in NMR, which is 83% of the 1H sensitivity, and has a strong dipole symmetry. By measuring the distance constraint between 19F-19F and 19F...

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Abstract

The invention discloses a multichannel three-dimensional nuclear magnetic resonance imaging method based on the 1H-19F-23Na atomic nucleus. A to-be-imaged part is scanned by using a multi-channel phased array coil and a magnetic resonance pulse sequence 1H / 23Na PANSY-COSY, <1>H / <19>F PANSY-COSY, 23Na-23NaCOSY, or 1H / 19F / 23Na PANSY-COSY, thereby obtaining a plurality of phased array coil images including a 23Na atomic nucleus image, a 1H atomic nucleus image, and a 19F atomic nucleus image; and registering and image fusion processing are carried out on the multiple phased array coil images to obtain a nuclear magnetic resonance image capable of providing tumour molecule information and metabolism information. According to the invention, the method not only has the great practical significance in early-stage diagnosis of a tumour, patient survival quality improvement, and tumour recovery rate enhancement but also has the important strategic significance in eliminating foreign medical technical restriction n, breaking the foreign medical technical monopoly, and taking the leading position in the medical iconography and oncology in the world.

Description

Technical field [0001] The invention relates to a nuclear magnetic resonance imaging method, in particular to a multi-channel three-dimensional nuclear magnetic resonance imaging method based on 1H-19F-23Na atomic nuclei. Background technique [0002] At present, nuclear magnetic resonance (NMR) imaging technology has been widely used in medical diagnosis. Nuclear magnetic resonance imaging is a biomagnetic nuclear spin imaging technology that has developed rapidly with the development of computer technology, electronic circuit technology, and superconductor technology. It uses magnetic fields and radio frequency pulses to resonate the precessing hydrogen nuclei (ie H+) in human tissues to generate radio frequency signals, which are then processed by a computer to image. Proton is the first choice for human imaging. Since various tissues of the human body contain a large amount of water and hydrocarbons, proton has high NMR sensitivity and strong signal. Therefore, people prefer ...

Claims

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Application Information

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IPC IPC(8): G01R33/44A61B5/055
CPCG01R33/44A61B5/055
Inventor 申宝忠
Owner HARBIN MEDICAL UNIVERSITY
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