Medicine composition for treating diabetic nephropathy and preparation method thereof

A technique for diabetic nephropathy and its composition, which is applied in the field of pharmaceutical composition for treating diabetic nephropathy and its preparation, and can solve problems such as drugs for diabetic nephropathy that have not yet been discovered

Inactive Publication Date: 2016-10-26
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, no very effective drug for diabetic nephropathy has been found

Method used

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  • Medicine composition for treating diabetic nephropathy and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: The pharmaceutical composition for the treatment of diabetic nephropathy and its preparation method

[0034] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating diabetic nephropathy are: 3300g of cinerea, 2600g of cedarflower leaves, 1900g of Budapest, 4500g of Humulus, 107g of methyl ursolic acid, and 71g of albinolin AA;

[0035] Preparation:

[0036] (1) According to the proportion of raw materials, take gray scallops, cedar sunflower leaves, knotweed, humulus, methyl ursolic acid, aspergillin AA, mix them evenly, and use ethanol with a concentration of 13% by weight as a solvent. 21 ℃ warm immersion extraction, the number of extractions is 11 times, each extraction time is 31 hours, and the amount of solvent used each time is 41.5 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, and extract A to recover ethanol , concentrated to a relative den...

Embodiment 2

[0039] Embodiment 2: the pharmaceutical composition for the treatment of diabetic nephropathy and its preparation method

[0040] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating diabetic nephropathy are: 3250g of cichlids, 2650g of cedarflower leaves, 1850g of knotweed, 4550g of humulus, 102g of methyl ursolic acid, and 76g of albinolin AA;

[0041] Preparation:

[0042] (1) According to the proportion of raw materials, take gray scallops, cedar sunflower leaves, knotweed, humulus, methyl ursolic acid, aspergillin AA, mix them evenly, and use ethanol with a concentration of 13% by weight as a solvent. 21 ℃ warm immersion extraction, the number of extractions is 11 times, each extraction time is 31 hours, and the amount of solvent used each time is 41.5 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, and extract A to recover ethanol , concentrated to a relative de...

Embodiment 3

[0045] Embodiment 3: the pharmaceutical composition for the treatment of diabetic nephropathy and preparation method thereof

[0046] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating diabetic nephropathy are: 3350g of cinerea, 2550g of cedarflower leaves, 1950g of Budapest, 4450g of Humulus, 112g of methyl ursolic acid, and 66g of albinolin AA;

[0047] Preparation:

[0048] (1) According to the proportion of raw materials, take gray scallops, cedar sunflower leaves, knotweed, humulus, methyl ursolic acid, aspergillin AA, mix them evenly, and use ethanol with a concentration of 13% by weight as a solvent. 21 ℃ warm immersion extraction, the number of extractions is 11 times, each extraction time is 31 hours, and the amount of solvent used each time is 41.5 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, and extract A to recover ethanol , concentrated to a relative...

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Abstract

The invention discloses a pharmaceutical composition for treating diabetic nephropathy and a preparation method thereof. The pharmaceutical composition of the invention is composed of gray sage, cedar sunflower leaves, knotweed, humulus, methyl ursolic acid, and pleinosaurin AA is the raw material medicine, which is prepared in proportion, and can be made into various dosage forms according to conventional preparation technology, and has remarkable curative effect in treating diabetic nephropathy.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating diabetic nephropathy and a preparation method thereof. Background technique [0002] According to reports, the incidence of chronic kidney disease in my country is increasing year by year, and it is estimated that the prevalence among adults has exceeded 10%, that is, there is one chronic kidney disease patient for every 10 people around us. What needs special attention is that in recent years, due to the high incidence of type 2 diabetes, the number of patients with diabetes and chronic kidney disease in my country has also increased sharply. According to Sun Yi, director of the Department of Urology at the Affiliated Central Hospital of Shenyang Medical College, in the 1980s, the proportion of diabetic nephropathy patients in my country was less than 4%, but today, this proportion has increased to more ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61P3/10A61P13/12A61K31/56A61K31/122
CPCA61K36/889A61K31/122A61K31/56A61K36/11A61K36/185A61K36/53A61K36/60A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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