Novel application of artemisinin ingredient or composition thereof in oral nursing

Abstract

The invention relates to novel application of an artemisinin ingredient or a composition thereof in oral nursing, namely novel application in the field of mammal oral nursing. The artemisinin ingredient or the composition has a series of advantages of capability of correcting keratinization abnormality, anti-inflammation effect, analgesic effect, hemostasis effect, callus effect, antibacterial effect and antifungal effect, thereby being capable of eliminating or relieving adverse conditions of mammal oral cavities to improve health and beauty of the oral cavities. The advantages are proved by obviously preventing or relieving mammal dental plaque, gingivitis, periodontitis, oral keratoma, tooth sensitivity, oral ulcer, dental decay and oral pathogen proliferation. The advantages are realized by applying the artemisinin ingredient or the composition thereof or oral nursing compositions like health products, daily chemical products, healthcare products or drugs containing the artemisinin ingredient or the composition thereof. Application of the artemisinin ingredient or the composition thereof is expanded to the field of oral nursing, so that the artemisinin ingredient or the composition thereof is enabled to exert higher efficacy for health cause of the public.

Description

technical field

[0001] The present invention relates to a new application of the defined artemisinin components or their composition, that is, the new application in the field of mammalian oral care includes, that is, by correcting abnormal keratosis, anti-inflammation, analgesia, hemostasis, healing Prevent, delay and / or treat mammalian dental plaque, gingivitis, periodontitis, oral keratosis, tooth sensitivity, oral ulcers, Dental caries, oral pathogenic bacteria proliferation and other adverse states, eliminate or relieve symptoms such as red, swollen and painful gums, bleeding gums, tooth pain, ulcers, and bad breath caused by them. These methods can be realized by applying oral care compositions such as health products, daily chemical products, health products or medicines containing safe and effective amounts of artemisinin components or their compositions to mammals that need such effects. benefit. Background technique

[0002] With the rapid development of economy ...

Examples

Embodiment 1

[0025] Embodiment 1: Artemisia annua toothpaste.

[0026] The following components can be made into artemisinin toothpaste through the existing production process of toothpaste.

Embodiment 2

[0027] Embodiment 2: artemisinin chewing gum.

[0028] The following components can be made into artemisinin chewing gum through the existing production process of chewing gum.

experiment example 1

[0029] Experimental Example 1: Anti-inflammatory effect of artemisinin components or compositions of the present invention

[0030] Artemisinin components or compositions thereof are dispersed in a pharmacologically acceptable matrix. Twenty-four Kunming mice were randomly divided into two groups, namely, the matrix control group and the 2% artemisinin-like component or its composition group, with 12 mice in each group. Apply 0.05 mL of xylene to the right ear of the mouse. After the stimulation, the same amount of matrix and 2% artemisinin or its combination were given locally to each group respectively at 15 min, 30 min, and 45 min. For the ear shells, use a puncher with a diameter of 8 mm to remove the ear pieces from the same part of the two ears to measure the mass, and calculate the swelling degree of the ear shells in each group based on the difference in mass between the two ear pieces for comparison.

[0031] Table 1. Effects of artemisinin components or their compos...

technical field

[0001] The present invention relates to a new application of the defined artemisinin components or their composition, that is, the new application in the field of mammalian oral care includes, that is, by correcting abnormal keratosis, anti-inflammation, analgesia, hemostasis, healing Prevent, delay and / or treat mammalian dental plaque, gingivitis, periodontitis, oral keratosis, tooth sensitivity, oral ulcers, Dental caries, oral pathogenic bacteria proliferation and other adverse states, eliminate or relieve symptoms such as red, swollen and painful gums, bleeding gums, tooth pain, ulcers, and bad breath caused by them. These methods can be realized by applying oral care compositions such as health products, daily chemical products, health products or medicines containing safe and effective amounts of artemisinin components or their compositions to mammals that need such effects. benefit. Background technique

[0002] With the rapid development of economy ...

Examples

Embodiment 1

[0025] Embodiment 1: Artemisia annua toothpaste.

[0026] The following components can be made into artemisinin toothpaste through the existing production process of toothpaste.

Embodiment 2

[0027] Embodiment 2: artemisinin chewing gum.

[0028] The following components can be made into artemisinin chewing gum through the existing production process of chewing gum.

experiment example 1

[0029] Experimental Example 1: Anti-inflammatory effect of artemisinin components or compositions of the present invention

[0030] Artemisinin components or compositions thereof are dispersed in a pharmacologically acceptable matrix. Twenty-four Kunming mice were randomly divided into two groups, namely, the matrix control group and the 2% artemisinin-like component or its composition group, with 12 mice in each group. Apply 0.05 mL of xylene to the right ear of the mouse. After the stimulation, the same amount of matrix and 2% artemisinin or its combination were given locally to each group respectively at 15 min, 30 min, and 45 min. For the ear shells, use a puncher with a diameter of 8 mm to remove the ear pieces from the same part of the two ears to measure the mass, and calculate the swelling degree of the ear shells in each group based on the difference in mass between the two ear pieces for comparison.

[0031] Table 1. Effects of artemisinin components or their compos...

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