Extract of diterpene-containing white flower cacalia seeds, extracting method of extract and application of extract

Abstract

The invention discloses an extract of diterpene-containing white flower cacalia seeds, an extracting method of the extract and an application of the extract. The extracting method includes the steps: drying the white flower cacalia seeds, crushing, sieving, extracting by alcoholic solution, and filtering to obtain total white flower cacalia seed alcohol extracting solution; performing decompression and concentration for the total white flower cacalia seed alcohol extracting solution to constant weight to obtain paste; sequentially extracting by cyclohexane and ethyl acetate to obtain an ethyl acetate extract. The ethyl acetate extract is the diterpene-containing white flower cacalia seed extract. The extract verifies that the extract of the white flower cacalia seeds containing ditepenoid compounds has good function of resisting chronic nonbacterial prostatitis. The white flower cacalia seeds are wide in distribution and easily obtained, the extract of the diterpene-containing white flower cacalia seeds is applied to preparation of medicines for preventing and treating chronic prostatitis, and a preparation method is simple and low in cost and meets development requirements of the medicines.

Description

technical field [0001] The invention belongs to the field of natural medicinal chemistry, and in particular relates to a diterpene-containing extract, an extraction method and an application thereof, which are obtained from Echeveria chinensis for the prevention and treatment of chronic prostatitis. Background technique [0002] (1) Research progress of prostatitis [0003] Chronic prostatitis (CP) is the most common disease in male urology. It is reported that the incidence rate in my country is 6.0%-32.9%, which is much higher than the incidence rate in foreign countries of 2.0%-16.0%. CP has complex etiology, protracted disease course, and variable symptoms, which seriously affect the physical and mental health of patients. The National Institute of Health (NIH) listed it as one of the most serious chronic diseases affecting the quality of life of residents. In 1995, the NIH divided prostatitis into four types: Type I: acute bacterial prostatitis (ABP); type II: chronic...

AI Technical Summary

Problems solved by technology

[0007] Currently, chemical drugs are mainly used to treat CABP / CPPS clinically, including antibiotics, α-reductase inhibitors, α-receptor blockers, non-steroidal anti-inflammatory drugs, neuromodulatory drugs, and immunosuppressive drugs. Drugs, vitamins and some trace elements, etc., but these drugs have certain side effects, and the clinical effect is also unsatisfactory.

Images