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Cat appeasing pheromone

一种信息素、组合物的技术，应用在药物组合、兽医用仪器、神经系统疾病等方向，能够解决没有描述猫安抚信息素等问题

Inactive Publication Date: 2017-02-22
INST OF INFORMATION CHEM & APPLIED ANIMAL BEHAVIOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, none of these patents describe soothing pheromones for cats

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0095] Example 1 - Isolation and analysis of components in feline secretions

[0096] Feline samples were obtained from the cat's skin by rubbing the compress between the shoulder blades and between the ears for 2 minutes. For analysis at time zero (T0) and day 14 (T14), the compress was rubbed from the scapula to the head of the cat. For sampling on day 28 (T28), half of the area from the scapula to the head was rubbed. The compress was then immediately placed in the flask and 4.0 g of dichloromethane was added. Collect the solvent with a glass pipette and spray it on the compress. This process was repeated 5 times. At the end of the fifth wash, samples were collected for chromatographic analysis.

[0097] The samples were then subjected to gas chromatography / mass spectrometry (GC / MS) using SHIMAZU QP 2010. Detection was done on impact at 200° CA at an energy usage (EI+) of 70 eV. A Supelco type DB column with a length of 30 m (id = 0.25 mm; membrane = 0.25 μm) was used...

Embodiment 2

[0104] Example 2 - Formulation of Feline Soothing Pheromones as Spot-on Preparations

[0105] use Feline soothing pheromones were formulated as described in Example 1 with 6 different fatty acid methyl esters. Combine 2 grams of cat soothing pheromones with 100 grams mix.

Embodiment 3

[0106] Example 3 - Test of cat soothing pheromones versus placebo

[0107] Sixteen cats were obtained for this example. The test has 6 different phases. Phase 0 was to take 16 cats and treat them with placebo or cat appeasement pheromone (CAP) for 10 minutes. Each experiment was performed using 2 cats at a time. 2 cats were housed in 2 different cages and placed in hallways. The corridor has a length of 5 meters and a width of 1.80 meters. The cages were then opened and the cats were allowed to roam freely in the corridors for 5 minutes, and their activities were observed during Phase 1. A pre-conflict period was observed in Phase 2, in which the cat was left alone in the hallway, but observed for 5 minutes. In Phase 3, a conflict of interest consisting of a bowl of food is introduced in the hallway. Place this bowl in the center of the hallway and watch the cat. In phase 4 is the beginning of the post-conflict period. Observation phases 3 and 4 lasted 5 minutes. In P...

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PUM

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Abstract

The present invention relates to a semiochemical composition comprising methyl palmitate, methyl linoleate, methyl oleate methyl stearate, methyl laurate, methyl myristate, salts thereof, derivatives thereof, isomers thereof and / or structural analogues thereof that have an appeasing effect in cats and / or also effects social facilitation in cats, and an acceptable vehicle. Solutions such as spot-on formulations of long duration are also encompassed. Methods to effect appeasing in a cat and / or social facilitation in cats are also disclosed.

Description

technical field [0001] The present invention relates to a semiochemical composition comprising methyl palmitate, methyl linoleate, methyl oleate, methyl stearate, methyl laurate, methyl myristate, Their salts, their derivatives, their isomers and / or structural analogs which have a soothing effect in cats or effect social facilitation in cats, and acceptable vehicles. The invention also includes solutions such as long duration spot-on formulations. Also disclosed are methods of achieving reassurance in cats and / or achieving social facilitation in cats. Background technique [0002] Cats have several modes of communication, such as visual communication for communicating emotions and interacting. These visual cues include body posture, expression, pupil size, fur erection, and tail position. An up-tail position is known to signal friendly intent when a cat approaches another animal or person, while a down-tucked tail between the legs often signals nervousness and / or submissi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/23A61K31/231A61K35/55A61P25/22
CPCA61K9/0017A61K31/23A61K31/231A61K35/55A61K47/10A61K2300/00A61P25/22A61D99/00
Inventor P·帕格特
Owner INST OF INFORMATION CHEM & APPLIED ANIMAL BEHAVIOR
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