Synthesis method of medicine intermediate carbamate compounds

A carbamate and synthesis method technology, applied in the field of pharmaceutical compound synthesis, can solve problems affecting the large-scale production and utilization of compounds, low product yield, environmental pollution, etc., and achieve good application prospects
CN106543040AActive Publication Date: 2017-03-29聊城高新区量子生物医药产业发展有限公司

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
聊城高新区量子生物医药产业发展有限公司
Publication Date
2017-03-29

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Abstract

The invention provides a synthesis method of medicine intermediate carbamate compounds. Compounds disclosed as Formula (I) and compounds disclosed as Formula (II) react in an organic solvent in the presence of a catalyst and a ligand to obtain carbamate compounds. The method implements high-yield synthesis of carbamate compounds, and has favorable application prospects.
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Description

technical field

[0001] The invention relates to a synthesis method of a pharmaceutical intermediate compound, more particularly to a synthesis method of a carbamate compound, and belongs to the field of synthesis of pharmaceutical compounds. Background technique

[0002] The carbamate structure is a very important class of active groups in organic chemical synthesis. It exists in various biologically active molecules and is one of the important skeleton structures of many pharmaceutically active compounds. Carbamate compounds, as intermediates in drug synthesis, can be expanded and modified through a variety of reactions to obtain biologically active compounds, which play an important role in organic chemical synthesis.

[0003] In recent years, more and more attention has been paid to the development of synthetic methods of carbamate compounds, a lot of research has been done on it, and some new synthetic routes and methods have been obtained. So far, various synthesis met...

Claims

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