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A technology of mixtures and extracts, applied in the direction of drug combinations, skin care preparations, skin diseases, etc., can solve problems such as unattractive and oily, insoluble active substances, etc.
Active Publication Date: 2017-05-10
BOOTS PURE DRUG CO LTD
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[0006] However, these actives are not soluble in water-based systems and may also be considered unattractive and oily if prepared in an oil-based system
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[0099] Skin penetration of dipeptides was measured in vitro using a Franz diffusion cell. Franz cell chambers are recognized in vitro skin penetration test devices to determine the extent of penetration of a given product into or through the skin. The Franz cell apparatus consists of two main chambers separated by a membrane. The membrane in this experiment was cut from a porcine skin sample and placed between the chambers of a Franz cell with an effective diffusion diameter of 0.9 cm. The receptor chamber had a volume of 4.2 ml and was filled with a receptor fluid consisting of 20% ethanol in water. Throughout the experiment, the contents of the receptor chamber were continuously stirred by a small magnetic stirrer. The skin temperature was maintained at 32°C by adjusting the water circulation system to 37°C. The donor chamber is open to atmosphere. Using a smooth spatula, 200 ml of the test composition containing the same peptide concentration was evenly applied to the s...
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Abstract
A water-in-oil emulsion comprising less than 60% water, and wherein said emulsion comprises an oil phase and a water phase, and wherein the water phase comprises a dipeptide selected from the group consisting of acetyl dipeptide (1) cetyl ester, acetyl dipeptide (3) aminohexanoate, azelaoyl bisdipeptide (10), coumaroyl dipeptide (3), dicetyl dipeptide (9), dipeptide diamino butyroyl benzylamide diacetate, dipeptide (1), dipeptide (10), dipeptide (11), dipeptide (12), dipeptide (15), dipeptide (16), dipeptide (17), dipeptide (18), dipeptide (19), dipeptide (2), dipeptide (20), dipeptide (3), dipeptide (4), dipeptide (5), dipeptide (6), dipeptide (7), dipeptide (8), dipeptide (8) HCL, dipeptide (9), hexanoyl dipeptide (3) norleucine acetate, methyl undecylenoyl dipeptide (16), nicotinoyl dipeptide (22), nicotinoyl dipeptide (23), nicotinoyl dipeptide (24), nicotinoyl dipeptide (26), oleoyl dipeptide (15), palmitoyl dipeptide (10), palmitoyl dipeptide (13), palmitoyl dipeptidel (7), palmitoyl dipeptide (5) diaminobutyroyl hydroxythreonine, palmitoyl dipeptide (5) diaminohydroxybutyrate, palmitoyl dipeptide (7) and mixtures thereof.
Description
technical field [0001] The invention relates to the field of cosmetics, in particular to a beauty lotion composition and a method for using the composition for skin beauty treatment. Background technique [0002] Cosmetic regimens and cosmetic treatments of the skin, especially of the face and neck, have become more common and more desirable. Such products are generally used primarily to improve the health and / or physical appearance of the skin. Many of these skin care products are concerned with delaying, reducing or even eliminating skin wrinkling and other typical histological changes that often accompany skin aging or environmental damage to human skin, such as photodamage. [0003] A number of skin care actives are known in the art for improving the health and / or physical appearance of the skin. For example, salicylic acid and benzoyl peroxide are used in skin care compositions to treat acne. Retinoids are another example of skin care formulations that are used in sk...
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