Combined marrow filter with multiple filtering functions

Abstract

The invention discloses a combined marrow filter with multiple filtering functions. The combined marrow filter comprises a beaker, a filtering connector, a connecting pipe, a collecting bag, a fixed cover, a filter shell, a limiting ring, a primary copper filter screen, a threaded ring, a secondary copper filter screen, a fixed sleeve, a vibrator and a sterile seal cover. The combined marrow filter with the multiple filtering functions is ingenious in structure and powerful in function, the built-in double filtering mechanisms are matched mutually and remarkably reduce fat and marrow debris, and the filtering effect is improved greatly; by means of a detachably collecting mechanism, marrow cell sap obtained after filtration can be collected conveniently, and the filtering effect can be improved in a slight oscillation mode according to needs; finally, the combined marrow filter with the multiple filtering functions brings great convenience to marrow cell filtration and is beneficial for clinical application and popularization.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a combined bone marrow filter with multiple filtering functions. Background technique [0002] Hematopoietic stem cell transplantation is currently an effective method for curing hematological malignancies. The transplantation modes include peripheral blood hematopoietic stem cell transplantation, bone marrow transplantation and mixed transplantation; bone marrow transplantation and mixed transplantation require collection of donor bone marrow hematopoietic stem cells. Generally, bone marrow collection is performed at the donor's posterior iliac or anterior superior iliac spine under epidural anesthesia. Bone marrow blood is collected with an empty needle, and the collection volume is 10-15ml / kg (recipient's body weight). In addition to blood cell components such as bone marrow hematopoietic stem cells, white blood cells, red blood cells, and platelets, there are also fat...

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Problems solved by technology

[0003] According to the above, the current routine clinical methods include filtering through a 200-300um filter or needle filtration (16-gauge and 9-gauge needles each). However, there are also the following problems: 1. After filter filtration and needle filtration, a large number of fat cells will remain due to the limited filtration efficiency; 2. The fully open environment may easily cause contamination of bone marrow hematopoietic stem cells; 3. Excessive needle filtration pressure will cause hematopoiesis Stem cells are destroyed, and it is easy to cause hemolysis of the recipient after infusion, even life-threatening. In view of the above defects, it is necessary to design a combined bone marrow filter with multiple filtering functions

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