Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Immunomodulatory composition for pregnant women and application thereof

A technology of immune regulation and composition, applied in the direction of application, food science, bacteria used in food preparation, etc., can solve the problems of low natural immune function of red blood cells, affecting the health of mothers and infants, and suppression of cellular immune function, so as to improve bowel function. Balance of intestinal microorganisms, improve immunity of pregnant women, and easy to absorb

Inactive Publication Date: 2018-05-29
GUANGZHOU PROFORCARE PHARMA INC
View PDF4 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Studies have shown that the cellular immune function of pregnant women is suppressed, and the natural immune function of red blood cells is significantly lower, making them susceptible to infection and affecting the health of mothers and babies.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Immunomodulatory composition for pregnant women and application thereof
  • Immunomodulatory composition for pregnant women and application thereof
  • Immunomodulatory composition for pregnant women and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-2 and comparative example 1-2

[0030] The components of the immunoregulatory probiotic composition of the present invention, in parts by weight, are as shown in Table 1:

[0031]

[0032]

[0033] Table 1

[0034] Among them, the above-mentioned Lactobacillus rhamnosus R11, Lactobacillus reuteri HA188 and Lactobacillus helveticus R52 are commercially available products, and the number of live bacteria is 7×10 10 -7.5×10 10 CFU / g; human milk-derived Lactobacillus fermentum CECT5716, commercially available, the number of live bacteria is 8.5×10 10 -9×10 10 CFU / g.

[0035] Weigh each material according to the formula ratio, dry at 60°C until the moisture content is lower than 3%, pass through a 60-mesh sieve, and mix evenly. It is prepared into solid beverage, chewable tablet or buccal tablet according to the conventional process in the industry.

Embodiment 3

[0036] Effect of embodiment 3 probiotic composition on immune function of pregnant mice

[0037] (1) Grouping and administration of experimental animals

[0038] Select a certain amount of Kunming mice aged about 2 months and weighing 20 ± 2g, female mice and male mice in the same cage at a ratio of 2:1, smear the vaginal secretions of the female mice on the next day, and if sperm is found, it is determined as Day 0 of pregnancy. Pregnant mice were randomly divided into blank group, test group and control group, wherein the test group was divided into four groups, and the probiotic compositions used corresponded to Example 1, Example 2, Example 3, Comparative Example 1 and Comparative Example 2 respectively. , 20 pregnant mice in each group. The blank group was given 37°C warm boiled water by gavage 3 times a day; the test group was gavaged 3 times a day with the probiotic composition solution described in Example 1, Example 2, Example 3, Comparative Example 1 and Comparativ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides an immunomodulatory composition for pregnant women, prepared from the following components in parts by weight: compound probiotic powder, lactobacillus fermentum CECT5716, cranberry juice powder, fructooligosaccharide and maltodextrin, wherein the compound probiotic powder is prepared from lactobacillus rhamnosus R11, lactobacillus reuteri HA188 and lactobacillus helveticusR52, and has a viable count of 6.0 to 8.5*10<10> CFU / g, and the lactobacillus fermentum CECT 576 has a viable count of 8.0 to 10.6*10<10> CFU / g. Food prepared from the above composition tastes good, and nutritious components are easily absorbed, so that the immunity of the pregnant women is obviously improved. A preparation method is simple, easy to operate and suitable for industrial production.

Description

technical field [0001] The invention relates to the field of functional food, in particular to an immunoregulatory composition for pregnant women and its application. Background technique [0002] In order to meet the physiological needs of pregnancy, pregnant women's endocrine regulation can make the body function in a state of low immune function. Studies have shown that the cellular immune function of pregnant women is suppressed, and the natural immune function of red blood cells is obviously low, which makes them susceptible to infection and affects the health of mothers and babies. Therefore, supplementary intake of vitamins, pantothenic acid, riboflavin, folic acid, taurine and trace elements is often used during pregnancy to improve immunity during pregnancy. [0003] However, a series of adaptive remodeling will occur in the maternal physiological state during pregnancy, and the imbalance of intestinal flora is also one of the important factors leading to complicat...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A23L19/00A23L33/125A23L33/135
CPCA23L19/01A23L33/125A23L33/135A23V2002/00A23V2400/147A23V2400/143A23V2400/173A23V2400/175A23V2200/3204A23V2200/324
Inventor 王晔陈蕾黄亮王从峰易晓敏
Owner GUANGZHOU PROFORCARE PHARMA INC
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com