Magnetic resonance quantitative imaging method and device based on gradient echoes

Abstract

The invention discloses a magnetic resonance quantitative imaging method and device based on gradient echoes. The method comprises the following steps: firstly, changing the echo time and the turnoverangle for many times to obtain K gradient echo signals, and acquiring the k space data on each coil channel of each gradient echo signal; and then according to the gradient echo signals, k space dataand phases on each coil, and the sensitivity of each coil channel, establishing unknown factors including a mathematical model of magnetic sensitivity, proton density, T1, and T*2, and finally solving the magnetic sensitivity, the proton density, T1, and T*2 corresponding to the minimization of the mathematical model. The magnetic resonance quantification is directly solved as the unknown in themathematical model, and the regularization is directly directed to the resonance quantification, a magnetic resonance quantitative value is obtained by solving an equation solution, and more accurateresults can be obtained. According to the method, the accuracy and accuracy of magnetic resonance quantification can be improved, and the accuracy of clinical diagnosis is further improved.

Description

technical field [0001] The present application relates to the technical field of magnetic resonance imaging, in particular to a gradient echo-based magnetic resonance quantitative imaging method and device. Background technique [0002] Magnetic resonance imaging (Magnetic Resonance Imaging, MRI), as a multi-parameter, multi-contrast imaging technology, is one of the main imaging methods in modern medical imaging, which can reflect various characteristics such as tissue T1, T2 and proton density. Provide information for disease detection and diagnosis. [0003] Traditional MRI images mainly consist of qualitative images of different contrast properties such as T 1 Weighted, T 2 weighting, proton density weighting, diffusion weighting, susceptibility weighting and more. But MRI images can provide far more than these qualitative information, it can also provide MRI quantitative information. The MRI quantitative information is more important for disease diagnosis, especiall...

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Problems solved by technology

[0005] However, the MRI quantitative images obtained by the above-mentioned traditional methods have the problems of low precision and low accuracy, which reduces the accuracy of clinical diagnosis.

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