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Method for improving disintegration time limit of fuke qianjin tablet

A technology of gynecological Qianjin tablet and Qianjinpu, which is applied in scientific instruments, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems affecting the clinical efficacy of gynecological Qianjin tablets, affecting the release of active ingredients, etc., and achieves improved clinical efficacy, Fast onset and short disintegration time

Inactive Publication Date: 2019-01-01
ZHUZHOU QIANJIN PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The applicant has concluded through a large number of long-term experiments that other active ingredients in Fuke Qianjin Tablets may affect the release of active ingredients, thereby affecting the clinical efficacy of Fuke Qianjin Tablets

Method used

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  • Method for improving disintegration time limit of fuke qianjin tablet
  • Method for improving disintegration time limit of fuke qianjin tablet
  • Method for improving disintegration time limit of fuke qianjin tablet

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Embodiment 1

[0032] The present invention will be further elaborated below in conjunction with specific examples, which are only used to explain the present invention, and are not intended to limit the scope of the present invention. The test methods used in the following examples are conventional methods unless otherwise specified; the materials and reagents used are commercially available reagents and materials unless otherwise specified. Example 1 Fuke Qianjin Tablets

[0033] Prepare Fukeqianjin Tablets by the following method:

[0034] The formula of Fukeqianjin Tablets: Angelica, Codonopsis, Andrographis paniculata and Shuangmianzhen each account for 9% of the total amount of medicinal materials; the dosages of Rosa japonica root, Caulis Spatholobus, Gongluomu and Qianjinba each account for 16% of the total amount of medicinal materials.

[0035] 1. Select Angelica, Codonopsis, and Andrographis paniculata, crush them into fine powders of more than 100 meshes, and keep them for later...

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Abstract

The invention discloses a method for improving disintegration time limit of fuke qianjin tablet. The fuke qianjin tablet is prepared from the following raw materials: philippine flemingia root, Chinese mahonia stem, herba andrographitis, folium zanthoxyli dissiti, caulis spatholobi, radix angelicae sinensis, radix codonopsis pilosulae and Cherokee rose root. During the preparation process of the fuke qianjin tablet, the content of Z-3-butylidene phthalide and the total volume of andrographolide and dehydrated andrographolide are regulated; in each fuke qianjin tablet, the content of Z-3-butylidene phthalide is not less than 0.015mg and the total volume of andrographolide and dehydrated andrographolide is not less than 1.1mg; HPLC method is optimally adopted for detecting the content. According to the invention, the important influences of the content of Z-3-butylidene phthalide and the total volume of andrographolide and dehydrated andrographolide in the fuke qianjin tablet on the product performances are confirmed and the accurate limitation is performed. Compared with the present fuke qianjin tablet, the fuke qianjin tablet prepared according to the invention has the advantages that the disintegration time limit is improved, the active ingredients are quickly released and can quickly take effect, and the clinical efficacy is further promoted.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a method for improving the disintegration time limit of Fukeqianjin Tablets. Background technique [0002] Fukeqianjin Tablets are medicines made from 8 medicinal materials, including Qianjinba, Rosa Radix, Andrographis paniculata, Gongluomu, Shuangmianzhen, Angelica, Millipede Spatholobus, and Codonopsis pilosula. The effect is to clear heat and dehumidify, tonify qi and blood. It is used for leukorrhea and abdominal pain caused by damp heat and blood stasis. Symptoms include profuse leukorrhagia, thick yellow matter, foul smell, lower abdomen pain, lumbosacral pain, mental fatigue and fatigue; chronic pelvic inflammatory disease, endometritis, Chronic cervicitis see the above syndrome. [0003] In the existing Chinese Pharmacopoeia, for the content identification of Fukeqianjin Tablets, only the total content of andrographolide and dehydroandrographolide ...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61K9/20A61P15/00G01N30/02
CPCA61K9/20A61K36/19A61K36/232A61K36/29A61K36/344A61K36/48A61K36/486A61K36/738A61K36/758A61K2236/331A61K2236/39A61P15/00G01N30/02G01N2030/027A61K2300/00
Inventor 龚云张鹏李伏君彭开锋凌勇根白璐袁红波何娟娟赵威
Owner ZHUZHOU QIANJIN PHARMA
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