Experimental device and method for artificial joint biological fixation interface micro-motion stimulation of bone growth
An artificial joint and experimental device technology, applied in the fields of biomedicine and tribology, can solve problems such as hindering the improvement and promotion of biological fixed artificial joints, and achieve the effects of shortening rehabilitation time, ensuring accuracy, and ensuring cell activity.
Active Publication Date: 2020-06-23
CHINA UNIV OF MINING & TECH
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Problems solved by technology
However, there is currently no experimental device for micromotion stimulation of bone tissue growth, which seriously hinders the improvement and promotion of biofixed artificial joints.
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[0031] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.
[0032] Such as figure 1 , figure 2 , image 3 An experimental device for stimulating bone growth by fretting at the biological fixation interface of an artificial joint shown in , including a voice coil motor module 1, a driving connecting rod 2, a biological environment incubator 3, a normal force loading module, and a friction measurement module group, slide module 6, biological medium container 7 and active bone fixture 8. The driving connecting rod 2 is rigidly connected to the voice coil motor module 1 and the sliding table module 6, and is responsible for transmitting the reciprocating motion of the voice coil motor module 1 to the sliding table module 6 with a micro-motion amplitude. The normal force loading module and the slide module 6 are completely sealed inside the biological environment incubator 3 .
[0033] The normal force loading m...
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The invention discloses an experimental device and method for stimulating bone growth through micro-motion of the biological fixation interface of an artificial joint. Based on the reconstruction function of bone trauma under mechanical stimulation, micro-motion stimulation is applied to the biological fixation interface after artificial joint replacement to accelerate the growth of the interface. Bone tissue grows and joins firmly. The experimental device includes a voice coil motor module, a driving connecting rod, a biological environment incubator, a normal force loading module, a friction measurement module, a sliding table module, a biological medium container, and an active bone fixture. The invention provides an experimental device for exploring the effects of micromotion on bone growth and bone damage at the biological fixation interface, and is of great significance for shortening the recovery time after artificial joint replacement, improving the solid quality of the artificial joint fixation interface, and extending the life of the artificial joint prosthesis.
Description
technical field [0001] The invention belongs to the technical fields of biomedicine and tribology, and in particular relates to an experimental device and method for stimulating bone growth by fretting at an artificial joint biological fixation interface. Background technique [0002] Artificial joint replacement has been widely used clinically since the 1960s, and has become the most successful and effective surgical and rehabilitation method for the treatment of human joint damage. After artificial joint replacement, the inactive artificial joint material and human bone should form a fixed interface. At present, the fixation methods are mainly divided into bone cement fixation and biological fixation (non-bone cement fixation). [0003] The biological fixation of artificial joint prosthesis does not require bone cement as a fixation medium, and completely relies on the natural healing between human bone tissue and artificial prosthesis materials, but the recovery time of b...
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IPC IPC(8): G01N33/00G01N33/483
CPCG01N33/00G01N33/4833G01N33/0078
Inventor张德坤徐寒冬陈凯张羽牛家墨张月茹
OwnerCHINA UNIV OF MINING & TECH