A drug compound for treating cholangiocarcinoma and its application

A drug compound and technology for cholangiocarcinoma, applied in the field of drug compound for the treatment of cholangiocarcinoma, can solve the problems of lack of treatment methods and poor prognosis, and achieve the effect of treating cholangiocarcinoma and delaying the progress of cholangiocarcinoma
CN109718235BActive Publication Date: 2021-07-20THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
Publication Date
2021-07-20

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Abstract

The invention relates to the field of pharmaceutical compositions, in particular to a pharmaceutical compound for treating cholangiocarcinoma and its application. A drug complex for treating cholangiocarcinoma, the basic active ingredient is composed of the following two drugs: a, levamisole or a pharmaceutically acceptable salt thereof; b, acitretin. The compound preparation is suitable for various solid tumors mainly manifested by hypoxia, such as cholangiocarcinoma. The results of cytological experiments on cholangiocarcinoma and the practice of clinical cases show that in terms of indications, the drug ingredients can produce obvious synergistic effects, significant curative effect, convenient and safe use, greatly reducing treatment costs, and are suitable for clinical use widely used.
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Description

technical field

[0001] The invention relates to the field of pharmaceutical compositions, in particular to a pharmaceutical compound for treating cholangiocarcinoma and its application. Background technique

[0002] Cholangiocarcinoma is the second most common malignant tumor of the hepatobiliary system after hepatocellular carcinoma. According to statistics, the overall mortality rate of hepatobiliary malignancies ranks fifth among all malignancies. my country is an area with a high incidence of cholangiocarcinoma, and the incidence has been increasing in recent years. It is more aggressive than hepatocellular carcinoma, only 30%-40% of patients can be effectively treated by surgical resection at the time of diagnosis, and most of the patients are already at an advanced stage when they are diagnosed, lacking effective treatment methods, and the prognosis is extremely poor Difference. Therefore, it is urgent to find new and effective treatment options.

[0003] Levamisol...

Claims

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