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Preparation method of compound spenceria ramalana and application thereof

A technology of rhubarb and compound recipes, which is applied in the field of preparation of anti-inflammatory and antidiarrheal Tibetan veterinary medicine compound rhizoma rhizome, and can solve problems such as blank development and utilization

Inactive Publication Date: 2019-05-21
SOUTHWEST UNIVERSITY FOR NATIONALITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the development and utilization of the compound Tibetan veterinary medicine, horseshoe yellow, for anti-inflammatory and antidiarrheal is almost blank in the vast Tibetan areas such as pastoral areas in northwestern Sichuan.

Method used

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  • Preparation method of compound spenceria ramalana and application thereof
  • Preparation method of compound spenceria ramalana and application thereof
  • Preparation method of compound spenceria ramalana and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 Extraction process of anti-inflammatory and anti-diarrheal Tibetan veterinary medicine compound horseshoe yellow total flavonoids

[0027] (1) The crushing of anti-inflammatory and anti-diarrheal Tibetan veterinary medicine compound horseshoe yellow prescription medicinal materials;

[0028] (2) Take 10 g of anti-inflammatory and anti-diarrheal Tibetan veterinary medicine compound horseshoe yellow prescription medicinal materials crushed in step (1), add 60% ethanol with a solid-liquid ratio of 1:20, and extract 3 times at 40 ° C, each time The leaching time is 60 minutes, the supernatants from the three extractions are combined, and the supernatants are concentrated under negative pressure at 70°C;

Embodiment 2

[0029] Example 2 Extraction process of anti-inflammatory and anti-diarrheal Tibetan veterinary medicine compound horseshoe yellow total flavonoids

[0030] (1) The crushing of anti-inflammatory and anti-diarrheal Tibetan veterinary medicine compound horseshoe yellow prescription medicinal materials;

[0031] (2) Take 10 g of anti-inflammatory and anti-diarrheal Tibetan veterinary medicine compound horseshoe yellow prescription medicinal materials crushed in step (1), add 60% ethanol with a solid-liquid ratio of 1:10, and extract 3 times at 50 ° C, each time The leaching time is 60 minutes, the supernatants from the three extractions are combined, and the supernatants are concentrated under negative pressure at 70°C;

Embodiment 3

[0032] Example 3 Extraction process of total flavonoids of anti-inflammatory and anti-diarrheal Tibetan veterinary compound recipe

[0033] (1) The crushing of anti-inflammatory and anti-diarrheal Tibetan veterinary medicine compound horseshoe yellow prescription medicinal materials;

[0034] (2) Take 10 g of anti-inflammatory and anti-diarrheal Tibetan veterinary medicine compound horseshoe yellow prescription medicinal material crushed in step (1), add 60% ethanol with a solid-liquid ratio of 1:20, and extract 3 times at 40 ° C, each time The leaching time is 50 minutes, the supernatants from the three extractions are combined, and the supernatants are concentrated under negative pressure at 70°C;

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Abstract

The invention discloses a preparation method of compound spenceria ramalana and an application thereof. The preparation method comprises the following steps of: (1) selecting spenceria ramalana, thalictrum delavayi, saussurea stella and rubus pungens as medicinal materials of anti-inflammatory antidiarrheal Tibetan veterinary drug compound spenceria ramalan, wherein the ratio is, by weight, 4:2:2:1, and crushing; (2) adding crushed medicinal materials to ethyl alcohol; extracting for 3 times, combining liquid supernatant of the 3 times of extraction; concentrating the liquid supernatant at 70DEG C under negative pressure; and obtaining concentrate of extract of general flavone of the anti-inflammatory antidiarrheal animal drug compound spenceria ramalan; and (3) purifying the concentrateby AB-8 macropore resin column for 1-5 times. The preparation method of the compound spenceria ramalana and the application thereof have the advantages of making full use of the advantages of Tibetanmedicine plant resources in northwestern Sichuan and other west areas, being capable of being widely used in prevention and treatment of diseases such as inflammatory diarrhea of yak and Tibetan sheep, and being good in therapeutic effect.

Description

technical field [0001] The invention relates to the technical field of veterinary medicines, in particular to a preparation method and application of anti-inflammatory and anti-diarrheal Tibetan veterinary compound horseshoe yellow. Background technique [0002] Animal husbandry is the main agricultural form and economic pillar in the pastoral areas of the western plateau of my country, especially in the three states of the western Sichuan plateau (including Ganzi, Aba and Liangshan in northwestern Sichuan) and Tibet. Common and frequently-occurring diseases of livestock and poultry in pastoral areas often break out in severe cold conditions. Among them, diarrheal diseases and parasitic diseases of young yaks and Tibetan sheep are more rampant, which not only seriously restricts the rapid development of animal husbandry in plateau pastoral areas, but also affects local areas. The improvement of herdsmen's quality of life and living standards has also caused adverse effects i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61P29/00A61P1/12A61P31/04
Inventor 陈朝喜汪露代弢
Owner SOUTHWEST UNIVERSITY FOR NATIONALITIES
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