Application of panax notoginseng total saponins combined with tanshinone IIA in preparation of drug for preventing colorectal cancer
A technology of Panax notoginseng saponins and colorectal cancer, applied in the field of traditional Chinese medicine, can solve the problems of clear adverse reactions, unapproved primary and secondary preventive drugs for colorectal cancer, etc., to promote tumor cell apoptosis and reduce cell survival rate , the effect of promoting apoptosis
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[0037] In order to make the technical means, creative features, goals and effects achieved by the present invention easy to understand, the present invention will be further described below in conjunction with specific embodiments.
[0038] 88 Balb / c male mice were randomly divided into 11 groups according to body weight, 8 in each group; they were AOM+DSS model control group, Panax notoginseng saponins+tanshinone ⅡA low dose group, notoginseng total saponins+tanshinone ⅡA Medium dose group, Panax notoginseng saponins+Tanshinone ⅡA high dose group, Panax notoginseng saponins low dose group, Panax notoginseng saponins medium dose group, Panax notoginseng saponins high dose group, Tanshinone ⅡA low dose group, Tanshinone ⅡA medium dose group , Tanshinone Ⅱ A high-dose group, blank control group. The first 10 groups were given intraperitoneal injection of AOM12.5mg / kg once, and the blank control group was injected with the same amount of 0.9% Nacl aqueous solution. The first 10 g...
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