Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for detecting ranitidine hydrochloride, cimetidine, famotidine, nizatidine and lafutidine

A technology of ranitidine hydrochloride and cimetidine, which can be used in measurement devices, instruments, scientific instruments, etc., can solve the problems of lack of quantitative methods and rapid product screening.

Inactive Publication Date: 2019-09-27
太原市食品药品检验所
View PDF2 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no quantitative method for this standard, and products produced by other manufacturers cannot be quickly screened according to this standard
In recent years, the applicant found that ranitidine hydrochloride and cimetidine were illegally added to Chinese patent medicines and health foods, and their similar drugs, famotidine, nizatidine, and lafutidine, also existed Possibility of being illegally added to health foods, Chinese patent medicines, or foods that illegally claim to have such functions

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for detecting ranitidine hydrochloride, cimetidine, famotidine, nizatidine and lafutidine
  • Method for detecting ranitidine hydrochloride, cimetidine, famotidine, nizatidine and lafutidine
  • Method for detecting ranitidine hydrochloride, cimetidine, famotidine, nizatidine and lafutidine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0048] Specific embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0049]This example provides a kind of Chinese patent medicine and health food that detects strengthening the stomach, improving gastrointestinal function (with auxiliary protective effect on gastric mucosal injury), and auxiliary protective function on gastric mucosal injury, or other foods that illegally claim such functions. Qualitative and quantitative detection methods for illegally added 5 chemical drugs including ranitidine hydrochloride, cimetidine, famotidine, nizatidine, and lafutidine. The principle of the method is as follows: the sample is extracted and diluted with methanol ultrasonically, separated by a C18 chromatographic column, and qualitatively and quantitatively analyzed by a liquid chromatography-mass spectrometer.

[0050] The specific method is as follows:

[0051] 1. Materials

[0052] 1.1. Instrument

[0053] Shimadz...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for detecting ranitidine hydrochloride, cimetidine, famotidine, nizatidine and lafutidine. The method comprises the following steps: (1) selecting chromatographic conditions; (2) selecting mass spectrometric conditions; (3) preparing a standard solution; (4), preparing samples; (5), detecting and calculating. Tests prove that the method is rapid and high in specificity; the method is suitable for detecting the illegally added ranitidine hydrochloride, famotidine, lafutidine, nizatidine, cimetidine and other chemical medicines in Chinese patent medicines and health-care foods which have the effects of invigorating the stomach, improving the gastrointestinal function (having an auxiliary protection effect on gastric mucosal injury) and having an auxiliary protection effect on gastric mucosal injury or in other foods illegally claimed to have said functions.

Description

technical field [0001] The invention relates to the field of food (including health food) and drug testing methods, specifically Chinese patent medicines and health food aimed at invigorating the stomach, improving gastrointestinal function (with auxiliary protective effect on gastric mucosal damage), and with auxiliary protective function on gastric mucosal damage , or other foods that illegally claim such functions are illegally added with five H 2 Qualitative and quantitative detection methods of receptor blockers. Background technique [0002] With the development of social economy and the quickening pace of life, gastric acid, stomach pain, gastric mucosal injury, gastric ulcer and other gastrointestinal diseases have become common diseases with a high incidence rate. Many people think that western medicine has a lot of side effects, and they are more willing to buy Chinese patent medicines and health food with mild side effects and less side effects, or some foods tha...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N30/06G01N30/88
CPCG01N30/06G01N30/88
Inventor 赵丽红李忠华
Owner 太原市食品药品检验所
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com