Fixing device for external exposure radiation experiment of buccal mucosa of mesocricetus auratus

A golden hamster and fixing device technology, which is applied in the fields of animal restraint equipment, medical science, veterinary equipment, etc., can solve the problems of blank special fixing equipment, inability to disengage, and inability to guarantee the personal safety of operators, so as to reduce the target tissue damage , The design is exquisite and light, and the operation is convenient and effective.

Pending Publication Date: 2019-12-10
ZHEJIANG CANCER HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Insufficiencies and defects of the commonly used devices: (1) The special fixing device is blank; (2) The conventional method depends on the skill of the operator; (3) It cannot be fixed for a long time; (4) It cannot be kept absolutely prohibited; (5) It cannot be separated from the hands (6) The personal safety of operators cannot be guaranteed

Method used

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  • Fixing device for external exposure radiation experiment of buccal mucosa of mesocricetus auratus
  • Fixing device for external exposure radiation experiment of buccal mucosa of mesocricetus auratus
  • Fixing device for external exposure radiation experiment of buccal mucosa of mesocricetus auratus

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Experimental program
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Effect test

Embodiment 1

[0015] Embodiment 1 A kind of golden hamster oral buccal mucosa external exposure irradiation experiment fixation device

[0016] refer to Figure 1-Figure 3 The invention provides a fixing device for the radiation experiment of the external exposure of the oral buccal mucosa of the golden hamster, aiming at solving the problem of fixing the radiation experiment of the external exposure of the oral mucosa of the golden hamster. The device of the present invention mainly adopts the principle of position-limiting clips. The device consists of a clamping table 1, a clamping ring 2, a lower A frame 3, an upper A frame 4, a frame shaft 5, an upper B frame 6, an elastic component 7, an upper hand ring 8, an upper piece 9, a lower hand ring 10, a lower piece 11, Shaft hole 12, lower B frame 13 and gorge 14 constitute. The clamping platform 1 made of sponge material is fixed on one end of the lower piece 11; the same end of the upper piece 9 extends downward to form a jagged edge, a...

Embodiment 2

[0018] Example 2 The use of a golden hamster oral and buccal mucosa external exposure irradiation experiment fixation device

[0019] 1. Fixed stage: refer to Figure 5 and Image 6 . After the hamster is anesthetized, touch the hamster's cheek pouch with fingers from outside to inside, turn out the inner mucosa from the mouth and pull it to form a dense mucous membrane group. Hold the upper hand ring 8 and the lower hand ring 10 of the other fixing device and apply relative pressure. After exceeding the resilience force of the spring 22, the other ends of the upper piece 9 and the lower piece 11 will be upturned with the frame shaft 5 as the fulcrum, that is, the upper piece The toothed edge of the lower edge of 9 is separated from the clamping platform 1, and the mucous membrane mass is inserted into the circular clamping ring 2 from the gorge 14, and the root of the mucosal mass is placed between the toothed edge of the upper piece 9 and the clamping platform 1 ; Release...

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Abstract

The invention provides a fixing device for an external exposure radiation experiment of the buccal mucosa of mesocricetus auratus. The fixing device comprises a clamping table, a clamping ring, a lower rack A, an upper rack A, a rack shaft, an upper rack B, an elastic component, an upper hand ring, an upper plate, a lower hand ring, a lower plate, an axle hole, a lower rack B and a gap, wherein the elastic component runs through the upper and lower plates to achieve an effect of supporting the upper and lower plates; and one end of the upper plate is protruded downward to form a serrated edgeand is placed on the clamping table. The fixing device can completely implement seizing and fixing on buccal mucosa tissues after the buccal mucosa of mesocricetus auratus is turned outward, and the serrated edge is safe and steady. The device is convenient and efficient in operation by utilizing the principle of a spacing clip; damage on a target tissue can be reduced by utilizing the elasticityof the spring and the material advantages of the clamping table; and the whole fixing device is smart and light in design, and can be transferred and irradiated together with an experimental object, so that irradiation damage of an operator can be prevented. The fixing device fills the blank of experimental equipment in the field.

Description

technical field [0001] The invention belongs to the field of auxiliary equipment for animal experiments, and relates to a fixing device for a golden hamster oral buccal mucosa external exposure radiation experiment, which is suitable for the fixing technology of the golden hamster oral mucosa external exposure radiation experiment. Background technique [0002] Golden hamster (hereinafter referred to as hamster), scientific name Mesocricetus auratus, English name Golden hamster. Hamsters have cheek pouches in their mouths that other rodents do not have. They can hide food on both sides of their gills and spit it out in a safe place for preservation. Therefore, hamsters have the largest proportion of oral mucosa area in other mice. Golden hamster is an important member of experimental animals, and ranks fourth among rodents after mice, rats and guinea pigs in terms of usage volume and usage range. Hamsters are susceptible to tumor-inducing viruses. Tumor tissues are easily ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D3/00
CPCA61D3/00
Inventor 陈媛媛张鹏舒泽凯陈明
Owner ZHEJIANG CANCER HOSPITAL
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