Methods, systems, and apparatus for reducing the frequency and/or severity of photophobic responses or for modulating circadian cycles

A technology of light reaction and equipment, applied in the direction of light therapy, optics, filter, etc.

CN111148482APending Publication Date: 2020-05-12UNIV OF UTAH RES FOUND
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2020-05-12

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Abstract

An optical filter may reduce the frequency and / or severity of photophobic responses or for modulating circadian cycles by controlling light exposure to cells in the human eye in certain wavelengths, such as 480nm and 590nm, and a visual spectral response of the human eye. The optical filter may disrupt the isomerization of melanopsin in the human eye reducing the availability of the active isoform, whereas the attenuation of light weighted across the action potential spectrum of the active isoform attenuates the phototransduction cascade leading to photophobic responses. Embodiments of an optical filter are described. In one embodiment an optical filter may be configured to transmit less than a first amount of light in certain wavelengths, and to transmit more than a second amount of lightweighted across the visual spectral response. Methods of use and methods of manufacturing optical filters are also described.
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Description

[0001] Cross References to Related Applications

[0002] This application claims the priority of U.S. Patent Application Serial No. 15 / 673,264, filed on August 9, 2017, entitled "METHODS, SYSTEMS, AND APPARATUS FOR REDUCING THE FREQUENCY AND / OR SEVERITY OFPHOTOPHOBIC RESPONSES OR FOR MODULATING CIRCADIAN CYCLES" rights, the entire disclosure of which is incorporated herein by reference. technical field

[0003] Photophobia or photosensitivity describes an adverse response to light that characterizes several neurological conditions. The present invention relates to managing the effects of light on objects. More specifically, the present invention relates to methods, systems and devices for reducing the frequency and / or severity of photophobic responses or for regulating the circadian cycle. Background technique

[0004] The retina of the eye contains various photoreceptor cells. These photoreceptor cells include rods (which are involved in black-and-white vision and low-li...

Examples

Embodiment Construction

[0059] Detailed descriptions of embodiments of the invention are provided herein. However, it should be understood that the present invention may be embodied in various forms. Therefore, specific details disclosed herein are not to be interpreted as limiting, but as a representative basis for teaching one skilled in the art how to employ the invention in virtually any detailed system, structure or manner.

[0060] The present invention relates to managing the effects of light on objects. Some applications of the invention relate to methods, systems and devices for reducing the frequency and / or severity of photophobic responses or for regulating the circadian cycle.

[0061]Different individuals experience photophobia in different ways. The wavelengths and thus pathways that trigger adverse reactions to light can vary from patient to patient. However, there are some common wavelengths that are more commonly associated with photophobia than others. For example, melanopsin ga...